
INTEGRATED-M-SC in Bio Science at Indian Institute of Technology Kharagpur

Paschim Medinipur, West Bengal
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About the Specialization
What is Bio Science at Indian Institute of Technology Kharagpur Paschim Medinipur?
This Integrated M.Sc. Biotechnology program at IIT Kharagpur focuses on a comprehensive understanding of biological processes, genetic engineering, bioprocess technology, and their applications. It integrates fundamental sciences with advanced biotechnological concepts, preparing students for innovation in the rapidly evolving Indian biotech sector. The program emphasizes both theoretical knowledge and practical skills crucial for industry and research. Its interdisciplinary approach equips graduates for diverse challenges.
Who Should Apply?
This program is ideal for scientifically inclined fresh graduates seeking entry into the diverse field of biotechnology. It also suits individuals with a strong background in biology, chemistry, or physics who aspire to contribute to healthcare, agriculture, and environmental solutions. Career changers transitioning into the biotech industry and those aiming for higher studies (PhD) in related disciplines will also find this program beneficial, with prerequisites often involving strong science aptitude.
Why Choose This Course?
Graduates of this program can expect promising career paths in biopharmaceutical companies, R&D labs, and agri-biotech firms in India. Entry-level salaries typically range from INR 6-10 LPA, with experienced professionals earning significantly more. The strong foundation also prepares students for roles in bioinformatics, clinical research, and entrepreneurship, aligning with the growing demand for skilled biotech professionals and potential for global careers. Professional certifications can also be pursued.

Student Success Practices
Foundation Stage
Master Core Scientific Principles- (Semester 1-2)
Focus rigorously on understanding fundamental concepts in Mathematics, Physics, Chemistry, and introductory Biology. Dedicate time daily to problem-solving and conceptual clarity, as these subjects form the bedrock for advanced biotechnology. Actively participate in laboratory sessions to build hands-on skills early.
Tools & Resources
NPTEL lectures, Khan Academy, Departmental tutorials, Study groups
Career Connection
A strong scientific foundation is crucial for grasping complex biotechnological concepts later, which directly impacts analytical skills needed for R&D and process development roles.
Cultivate Analytical & Laboratory Skills- (Semester 1-2)
Engage proactively in all laboratory courses. Understand the theoretical basis of each experiment and meticulously follow protocols. Develop accurate data recording and interpretation skills. Seek opportunities for extra lab time or assisting senior students to gain more hands-on experience in basic biochemical techniques.
Tools & Resources
Lab manuals, Faculty guidance, Online videos (e.g., YouTube), Peer mentorship
Career Connection
Proficiency in lab techniques is non-negotiable for research, quality control, and process development roles in the biotech industry, significantly enhancing employability.
Develop Effective Study Habits & Networking- (Semester 1-2)
Establish a consistent study routine, review lecture notes regularly, and prepare for exams systematically. Join or form study groups to discuss challenging topics and learn from peers. Attend introductory seminars and interact with senior students and faculty to understand various sub-fields within biotechnology.
Tools & Resources
Personal planners, Academic calendars, Campus library resources, Student clubs
Career Connection
Strong academic performance lays the groundwork for advanced courses and internships. Early networking helps identify mentors and potential career paths, valuable for future job searches and collaborations.
Intermediate Stage
Dive Deep into Core Biotech Disciplines- (Semester 3-5)
Focus intensely on subjects like Genetics, Microbiology, Biochemistry, Molecular Biology, and Bioprocess Engineering. Seek to connect theoretical knowledge with practical applications. Explore research papers and case studies related to course topics to broaden understanding and critical thinking.
Tools & Resources
PubMed, Google Scholar, Biotechnology journals, Advanced textbooks
Career Connection
A deep understanding of these core areas is directly applicable to specialized roles in R&D, manufacturing, and quality assurance within pharmaceutical, agricultural, and industrial biotech sectors.
Gain Practical Experience via Internships & Projects- (Semester 3-5)
Actively seek summer internships (both academic and industrial) after semesters 4 and 6. Participate in departmental research projects under faculty supervision. Apply learned concepts to real-world problems and develop problem-solving skills, which are highly valued by employers in the Indian biotech landscape.
Tools & Resources
Career Development Centre (CDC), Faculty network, LinkedIn, Industry job boards
Career Connection
Internships provide critical industry exposure, build a professional network, and often lead to pre-placement offers, significantly boosting placement prospects. Project work showcases practical abilities.
Develop Specialized Skills in Bioinformatics- (Semester 3-5)
Recognize the growing importance of computational biology. Take bioinformatics courses seriously and develop proficiency in data analysis, programming (e.g., Python, R), and using bioinformatics tools and databases. Work on small computational projects to build a portfolio.
Tools & Resources
NCBI databases (GenBank), Python/R programming, Online bioinformatics tutorials, Open-source software
Career Connection
Bioinformatics skills are in high demand across biotech, pharma, and healthcare for drug discovery, genomics, and personalized medicine, opening up diverse and high-paying roles.
Advanced Stage
Master Advanced & Applied Biotechnology- (Semester 6-8)
Focus on specialized areas like Genetic Engineering, Pharmaceutical Biotechnology, Environmental Biotechnology, and Downstream Processing. Choose departmental electives wisely to build expertise in areas of personal interest and career aspiration. Engage in advanced lab techniques and independent project work.
Tools & Resources
Advanced research papers, Industry reports, Specialized software for bioprocess simulation, Patent databases
Career Connection
Deep specialization makes you highly desirable for specific roles in R&D, product development, and manufacturing. Expertise in regulatory affairs and IP is also key for product commercialization.
Engage in Advanced Research Projects & Internship- (Semester 6-8)
Initiate and dedicate significant effort to Research Project I (Semester 6) and Research Project II (Semester 7), aiming for innovative problem-solving. Actively seek and complete the mandatory Industrial Training/Internship in Semester 8, applying classroom knowledge to real-world industrial settings and gaining practical insights into operations.
Tools & Resources
Research mentors, University research facilities, Industry contacts from faculty, Internship portals
Career Connection
Demonstrating strong research capabilities and practical industry experience through these projects and internships is crucial for securing top placements and prepares students for the rigorous demands of final year thesis work.
Develop Professional & Entrepreneurial Acumen- (Semester 6-8)
Enhance presentation, report writing, and communication skills through project reports. Attend workshops on IPR, Bioethics, and Biosafety, understanding their significance in the biotech industry. For those inclined, explore the Bio-Entrepreneurship & Management course seriously to develop business acumen and innovation ideas for startup ventures.
Tools & Resources
Communication skill workshops, IPR workshops, Department''''s entrepreneurial cell, Business plan competitions
Career Connection
Strong soft skills, ethical understanding, and an entrepreneurial mindset are vital for leadership roles, driving innovation, and successfully navigating the complex regulatory landscape of the biotech industry in India.
Program Structure and Curriculum
Eligibility:
- Through JEE Advanced
Duration: 10 semesters / 5 years
Credits: 199 Credits
Assessment: Assessment pattern not specified
Semester-wise Curriculum Table
Semester 1
| Subject Code | Subject Name | Subject Type | Credits | Key Topics |
|---|---|---|---|---|
| MA11001 | Mathematics I | Core | 4 | Single Variable Calculus, Sequences and Series, Mean Value Theorems, Improper Integrals, Limits and Continuity |
| PH11001 | Physics I | Core | 4 | Mechanics, Newtonian Laws, Work and Energy, Oscillations and Waves, Special Relativity |
| CY11001 | Chemistry I | Core | 4 | Atomic Structure and Quantum Mechanics, Chemical Bonding, Organic Reaction Mechanisms, Stereochemistry, Basic Thermodynamics |
| BT11001 | Introduction to Biotechnology | Core | 3 | History and Scope of Biotechnology, Cell Biology Basics, Overview of Genetic Engineering, Applications in Medicine and Agriculture, Ethical Considerations |
| HS10001 | English for Communication | Core | 2 | Grammar and Vocabulary, Reading Comprehension, Technical Writing, Presentation Skills, Effective Communication |
| BT19001 | Biotechnology Lab I | Lab | 2 | Basic Biochemical Techniques, Microscopy, Aseptic Handling, Spectrophotometry, Preparation of Solutions |
| PH19001 | Physics Lab I | Lab | 2 | Experiments in Mechanics, Oscillations, Error Analysis, Data Interpretation, Use of Basic Instruments |
| CY19001 | Chemistry Lab I | Lab | 2 | Volumetric Analysis, Organic Compound Synthesis, Qualitative Analysis, Recrystallization, Chromatography |
Semester 2
| Subject Code | Subject Name | Subject Type | Credits | Key Topics |
|---|---|---|---|---|
| MA12001 | Mathematics II | Core | 4 | Multivariable Calculus, Vector Calculus, Partial Derivatives, Multiple Integrals, Line and Surface Integrals |
| PH12001 | Physics II | Core | 4 | Electromagnetism, Maxwell''''s Equations, Optics, Quantum Phenomena, Solid State Physics Basics |
| CY12001 | Chemistry II | Core | 4 | Chemical Thermodynamics, Chemical Kinetics, Electrochemistry, Transition Metal Chemistry, Polymer Chemistry |
| BT12001 | Biochemistry | Core | 3 | Biomolecules (Proteins, Carbohydrates, Lipids), Enzyme Kinetics, Metabolic Pathways, Bioenergetics, Vitamins and Hormones |
| BS10001 | Environmental Studies | Core | 2 | Ecosystems and Biogeochemical Cycles, Biodiversity and Conservation, Environmental Pollution, Sustainable Development, Climate Change |
| BT19002 | Biotechnology Lab II | Lab | 2 | Enzyme Assays, Protein Estimation, Chromatographic Techniques, Gel Electrophoresis, Cell Fractionation |
| PH19002 | Physics Lab II | Lab | 2 | Experiments in Electricity, Magnetism, Optics, Semiconductors, Spectroscopy |
| CY19002 | Chemistry Lab II | Lab | 2 | Physical Chemistry Experiments, Chemical Kinetics, Electrochemistry Measurements, Acid-Base Titrations, Thermochemistry |
Semester 3
| Subject Code | Subject Name | Subject Type | Credits | Key Topics |
|---|---|---|---|---|
| MA21001 | Mathematics III | Core | 4 | Ordinary Differential Equations, Partial Differential Equations, Linear Algebra, Fourier Series, Laplace Transforms |
| BT21001 | Genetics | Core | 3 | Mendelian Genetics, Gene Interaction, Population Genetics, Chromosomal Aberrations, Molecular Genetics |
| BT21002 | Microbiology | Core | 3 | Microbial Diversity, Bacterial Growth and Metabolism, Virology, Antimicrobial Agents, Industrial Microbiology |
| BT21003 | Cell Biology | Core | 3 | Cell Structure and Organelles, Cell Cycle and Division, Cell Communication, Membrane Transport, Cellular Pathology |
| ID20001 | Science of Living | Core | 3 | Introduction to Biological Systems, Human Physiology Basics, Diversity of Life, Evolutionary Biology, Ecological Principles |
| HSXXX | Humanities & Social Sciences Elective I | Elective | 3 | Microeconomics, Psychology, Sociology, Ethics, History of Science |
| BT29001 | Biotechnology Lab III | Lab | 2 | Microbial Culture Techniques, Bacterial Staining, Sterilization Methods, Yeast Genetics Experiments, Basic Immunological Techniques |
Semester 4
| Subject Code | Subject Name | Subject Type | Credits | Key Topics |
|---|---|---|---|---|
| BT22001 | Molecular Biology | Core | 3 | DNA Replication, Transcription and Translation, Gene Regulation (Prokaryotic & Eukaryotic), Recombination and DNA Repair, Epigenetics |
| BT22002 | Immunology | Core | 3 | Innate and Adaptive Immunity, Antibody Structure and Function, Antigen Presentation, Vaccinology, Hypersensitivity and Autoimmunity |
| BT22003 | Bioprocess Engineering | Core | 4 | Bioreactor Design and Operation, Mass and Energy Balances, Sterilization Techniques, Fermentation Technology, Product Recovery Principles |
| BT22004 | Bioinformatics | Core | 3 | Sequence Alignment, Genomics and Proteomics, Phylogenetic Analysis, Drug Design Principles, Biological Databases and Tools |
| BT22005 | Animal Cell & Tissue Culture | Core | 3 | Principles of Cell Culture, Culture Media and Supplements, Aseptic Techniques, Cell Line Maintenance, Applications in Research |
| BT29002 | Molecular Biology Lab | Lab | 2 | DNA/RNA Extraction, PCR and RT-PCR, Agarose Gel Electrophoresis, Restriction Digestion, Blotting Techniques |
| BT29003 | Bioprocess Engineering Lab | Lab | 2 | Bioreactor Operation, Enzyme Immobilization, Fermentation Monitoring, Product Separation Techniques, Sterilization Validation |
Semester 5
| Subject Code | Subject Name | Subject Type | Credits | Key Topics |
|---|---|---|---|---|
| BT31001 | Genetic Engineering | Core | 3 | Recombinant DNA Technology, Cloning Vectors, Gene Editing (CRISPR-Cas9), Gene Transfer Methods, Applications in Gene Therapy |
| BT31002 | Plant Biotechnology | Core | 3 | Plant Tissue Culture, Micropropagation, Transgenic Plants, Crop Improvement, Plant Secondary Metabolites |
| BT31003 | Downstream Processing | Core | 3 | Cell Disruption Methods, Filtration and Centrifugation, Chromatographic Separations, Protein Purification Strategies, Product Formulation |
| BT31XXX | Departmental Elective I | Elective | 3 | Nanobiotechnology, Stem Cell Biology, Biosensors, Drug Delivery Systems, Immunodiagnostics |
| OE31XXX | Open Elective I | Elective | 3 | Introduction to AI, Principles of Management, Environmental Law, Computational Methods, Design Thinking |
| BT39001 | Genetic Engineering Lab | Lab | 2 | Plasmid Isolation, Restriction Ligation, Bacterial Transformation, Colony PCR, Gene Expression Analysis |
| BT39002 | Plant Tissue Culture Lab | Lab | 2 | Micropropagation Techniques, Callus Culture, Protoplast Isolation, Agrobacterium-mediated Transformation, Gene Transfer in Plants |
Semester 6
| Subject Code | Subject Name | Subject Type | Credits | Key Topics |
|---|---|---|---|---|
| BT32001 | Pharmaceutical Biotechnology | Core | 3 | Biopharmaceuticals Production, Drug Delivery Systems, Clinical Trials and Regulations, Vaccine Development, Antibody Engineering |
| BT32002 | Environmental Biotechnology | Core | 3 | Bioremediation, Wastewater Treatment, Bioenergy Production, Pollution Control, Microbial Ecology |
| BT32003 | IPR, Bioethics & Biosafety | Core | 3 | Intellectual Property Rights (Patents, Trademarks), Ethical Issues in Biotechnology, Biosafety Guidelines and Regulations, Genetically Modified Organisms, Regulatory Agencies |
| BT32XXX | Departmental Elective II | Elective | 3 | Computational Biology, Metabolic Engineering, Biomaterials, Synthetic Biology, Advanced Genomics |
| HSXXX | Humanities & Social Sciences Elective II | Elective | 3 | Organizational Behavior, Entrepreneurship Development, Public Administration, Managerial Economics, Indian Culture and Society |
| BT39003 | Environmental Biotechnology Lab | Lab | 2 | Water Quality Analysis, Biosorption Experiments, Microbial Fuel Cells, Bioreactor for Waste Treatment, Heavy Metal Bioremediation |
| BT39004 | Research Project I | Project | 3 | Literature Review, Experimental Design, Methodology Development, Preliminary Data Collection, Technical Report Writing |
Semester 7
| Subject Code | Subject Name | Subject Type | Credits | Key Topics |
|---|---|---|---|---|
| BT41001 | Systems Biology | Core | 3 | Omics Technologies (Genomics, Proteomics), Network Biology, Mathematical Modeling of Biological Systems, Computational Tools for Systems Biology, Drug Discovery using Systems Biology |
| BT41XXX | Departmental Elective III | Elective | 3 | Industrial Biotechnology, Food Biotechnology, Marine Biotechnology, Medical Devices, Biorefinery Concepts |
| BT41XXX | Departmental Elective IV | Elective | 3 | Biofuel Production, Advanced Immunology, Neurobiotechnology, Structural Biology, Protein Engineering |
| OE41XXX | Open Elective II | Elective | 3 | Machine Learning Basics, Financial Management, Operations Research, Cybersecurity Fundamentals, Product Design |
| BT49001 | Advanced Biotechnology Lab | Lab | 4 | Advanced Molecular Cloning, Cell Culture Applications, Protein Expression and Purification, Immunoassays (ELISA, Western Blot), Spectroscopic Techniques |
| BT49002 | Research Project II | Project | 3 | Data Analysis and Interpretation, Statistical Methods, Scientific Writing, Oral Presentation of Results, Troubleshooting Experimental Issues |
Semester 8
| Subject Code | Subject Name | Subject Type | Credits | Key Topics |
|---|---|---|---|---|
| BT42001 | Bio-Entrepreneurship & Management | Core | 3 | Business Plan Development, Startup Ecosystem in India, Funding and Venture Capital, Marketing Strategies for Biotech Products, IP Management and Commercialization |
| BT42XXX | Departmental Elective V | Elective | 3 | Genomics and Proteomics, Biomarkers in Disease, Forensic Biotechnology, Vaccine Technology, Regenerative Medicine |
| BT42XXX | Departmental Elective VI | Elective | 3 | Cancer Biology, Neuroscience, Microbial Genomics, Food Processing Technology, Biophotonics |
| HSXXX | Humanities & Social Sciences Elective III | Elective | 3 | Human Resource Management, Project Management, Technology and Society, Consumer Behavior, Ethics in Business |
| BT49003 | Industrial Training/Internship | Project | 6 | Industry Exposure, Practical Skill Application, Report Writing, Professional Networking, Problem-Solving in Industry |
Semester 9
| Subject Code | Subject Name | Subject Type | Credits | Key Topics |
|---|---|---|---|---|
| BT51001 | Advanced Biostatistics | Core | 3 | Experimental Design, Hypothesis Testing, Regression Analysis, Multivariate Statistics, Statistical Software (R, SPSS) |
| BT51XXX | Departmental Elective VII | Elective | 3 | Translational Biotechnology, Clinical Proteomics, Personalized Medicine, Immunoinformatics, Advanced Enzyme Technology |
| BT51XXX | Departmental Elective VIII | Elective | 3 | Bioimaging and Microscopy, Drug Discovery and Development, CRISPR Technology, Tissue Engineering, Advanced Vaccine Delivery |
| OE51XXX | Open Elective III | Elective | 3 | Data Science Principles, Supply Chain Management, Intellectual Property Law, Sustainable Engineering, Communication Systems |
| BT59001 | Thesis Part I / Major Project | Project | 6 | In-depth Literature Review, Research Proposal Development, Experimental Design and Execution, Data Collection, Initial Report Preparation |
Semester 10
| Subject Code | Subject Name | Subject Type | Credits | Key Topics |
|---|---|---|---|---|
| BT52001 | Regulatory Affairs & Quality Control | Core | 3 | Good Manufacturing Practices (GMP), Good Laboratory Practices (GLP), Quality Assurance and Control, Biotechnology Product Regulations, Documentation and Auditing |
| BT52XXX | Departmental Elective IX | Elective | 3 | Advanced Virology, Parasitology, Bioethics in Research, Bioinstrumentation, Applied Statistics for Biotech |
| BT52XXX | Departmental Elective X | Elective | 3 | Food Safety and Quality, Agri-biotechnology Policy, Bioinformatics Algorithms, Drug Repurposing, Biomedical Engineering Interfaces |
| BT59002 | Thesis Part II / Major Project | Project | 9 | Advanced Data Analysis, Interpretation of Results, Thesis Writing and Formatting, Oral Defense Preparation, Scientific Publication Strategies |




