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B-TECH-M-TECH in Biotechnology Engineering at Kalinga Institute of Industrial Technology
Khordha, Odisha
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About the Specialization
What is Biotechnology Engineering at Kalinga Institute of Industrial Technology Khordha?
This Biotechnology Engineering program at Kalinga Institute of Industrial Technology focuses on integrating biological sciences with engineering principles to develop innovative solutions for various sectors. With India''''s rapidly growing biotechnology sector in areas like pharmaceuticals, agriculture, and healthcare, this dual degree program is designed to create highly skilled professionals capable of driving scientific and industrial advancements. It emphasizes both fundamental understanding and practical application, preparing students for impactful careers.
Who Should Apply?
This program is ideal for high school graduates with a strong foundation in science, particularly biology and mathematics, who are passionate about applying scientific knowledge to real-world problems. It suits those aspiring to work in research and development, biopharmaceutical manufacturing, or environmental biotechnology. Working professionals seeking to upskill in advanced biotech domains or career changers transitioning into the dynamic Indian biotech industry will also find this program highly beneficial.
Why Choose This Course?
Graduates of this program can expect diverse India-specific career paths, including roles as R&D scientists, bioprocess engineers, quality control specialists, or bio-entrepreneurs in companies like Biocon, Dr. Reddy''''s Laboratories, or Serum Institute of India. Entry-level salaries typically range from INR 4-7 LPA, growing significantly with experience. The program equips students with interdisciplinary skills, aligning with certifications in bioprocess technology, regulatory affairs, or intellectual property rights, enhancing their growth trajectory.
Student Success Practices
Foundation Stage
Master Core Science and Math Fundamentals- (Semester 1-2)
Dedicate time to thoroughly understand foundational subjects like Biology, Chemistry, Physics, and Engineering Mathematics. These form the bedrock for advanced biotechnology concepts. Utilize online platforms like Khan Academy for conceptual clarity and problem-solving. Form study groups with peers to discuss challenging topics and solve problems collaboratively, strengthening collective understanding.
Tools & Resources
Khan Academy, NPTEL videos for basic engineering sciences, Peer study groups
Career Connection
A strong foundation ensures easier grasp of complex biotech subjects later, crucial for excelling in technical interviews and research roles in core biotech companies.
Develop Foundational Programming Skills- (Semester 1-2)
Engage actively in programming courses (e.g., C, Python) and practice coding regularly. Use online coding platforms like HackerRank or CodeChef to hone problem-solving skills through competitive programming. This will build a computational mindset essential for bioinformatics and data analysis in biotechnology.
Tools & Resources
HackerRank, CodeChef, GeeksforGeeks, Python tutorials
Career Connection
Proficiency in coding enhances employability for roles in bioinformatics, computational biology, and R&D data analysis, which are increasingly in demand in the Indian biotech industry.
Actively Participate in Basic Science Labs- (Semester 1-2)
Treat laboratory sessions not just as compulsory tasks but as opportunities for hands-on learning. Ask questions, understand the ''''why'''' behind each step, and maintain meticulous lab records. Explore supplementary experiments or demonstrations available through department resources or online simulations.
Tools & Resources
Lab manuals, Online lab simulations (e.g., Virtual Labs from MHRD), Department faculty
Career Connection
Developing strong practical skills and a keen observational eye early on is vital for future research, experimental design, and quality control roles in biotech firms.
Intermediate Stage
Engage in Departmental Research Projects- (Semester 3-5)
Seek out opportunities to work on small research projects with faculty members in semesters 3-5. These can be independent studies, literature reviews, or assisting ongoing lab work. This provides early exposure to scientific methodology and builds a research portfolio. Attend departmental seminars to understand ongoing research areas.
Tools & Resources
Departmental faculty, Research labs, Scientific journals
Career Connection
Early research experience significantly boosts applications for internships, higher studies (M.Tech/PhD), and entry-level R&D positions, offering a competitive edge in India''''s academic and industrial research landscape.
Pursue Internships and Industrial Training- (Summer breaks after Semesters 4 and 6)
Actively search for summer internships or industrial training programs in biotech companies, research institutes (e.g., CCMB, CDFD), or pharmaceutical firms. Focus on gaining practical exposure to bioprocesses, genetic engineering, or bioinformatics. Leverage KIIT''''s strong industry connections and alumni network.
Tools & Resources
KIIT Placement Cell, LinkedIn, Internshala, Alumni network
Career Connection
Internships are critical for networking, understanding industry demands, and often lead to pre-placement offers, streamlining your entry into India''''s biotech job market.
Build Specialized Skill Sets through Online Courses- (Semester 3-5)
Complement coursework with online certifications in areas like Bioprocess Technology, Bioinformatics (e.g., R, Python for Biologists), Genetic Engineering techniques, or Machine Learning in Biology. Platforms like Coursera, edX, or NPTEL offer specialized modules to deepen knowledge beyond the curriculum.
Tools & Resources
Coursera, edX, NPTEL, Udemy
Career Connection
Demonstrating specialized skills via certifications makes you a more attractive candidate for niche roles in drug discovery, data science in healthcare, or advanced manufacturing within Indian and global MNCs.
Advanced Stage
Intensify Major Project Work and Thesis Development- (Semester 7-10)
Treat your B.Tech and M.Tech thesis projects as a capstone experience. Focus on a clear problem statement, rigorous experimental design, data analysis, and meticulous scientific writing. Aim for publishing your work in peer-reviewed journals or presenting at national conferences to showcase your research capabilities.
Tools & Resources
Research Supervisors, Library resources, Statistical software (R, Python), LaTeX/Word
Career Connection
A strong thesis and publication record are invaluable for securing R&D positions, scholarships for higher studies abroad, or successful entrepreneurship ventures in India.
Network and Prepare for Placements/Further Studies- (Semester 8-10)
Attend career fairs, workshops, and guest lectures hosted by the university. Actively network with industry professionals and alumni. Prepare a tailored resume, practice group discussions, and mock interviews. For higher studies, focus on GRE/GATE preparation, statement of purpose, and recommendation letters.
Tools & Resources
KIIT Placement Cell, Career Services, Online interview platforms, GATE/GRE coaching
Career Connection
Effective networking and comprehensive preparation are key to securing coveted positions in Indian and international biotech firms, or gaining admission to top-tier graduate programs.
Develop Soft Skills and Leadership Qualities- (Throughout all semesters, with increased focus in later years)
Actively participate in student clubs, technical societies, and organizational events to develop communication, teamwork, and leadership skills. These are highly valued by employers alongside technical expertise. Take on leadership roles in projects or student bodies to build experience in managing teams and initiatives.
Tools & Resources
Student Clubs and Societies (e.g., Biotech Society), Workshops on soft skills, Public speaking forums
Career Connection
Strong soft skills enable effective collaboration in interdisciplinary biotech teams, leadership in project management, and success in client-facing or managerial roles in the Indian biotech industry.
Program Structure and Curriculum
Eligibility:
- Passed 10+2 or equivalent examination in 2022, 2023 or appearing in 2024 with a minimum of 60% marks in aggregate. Should have studied Physics, Chemistry, and Mathematics (PCM) and/or Biology/Biotechnology (PCMB) in 10+2 with a minimum of 45% marks in Physics, Chemistry, and Mathematics/Biology/Biotechnology taken together. Age: Not more than 21 years old as on 01.07.2024.
Duration: 5 Years (10 Semesters)
Credits: 226 Credits
Assessment: Internal: 50%, External: 50%
Semester-wise Curriculum Table
Semester 1
| Subject Code | Subject Name | Subject Type | Credits | Key Topics |
|---|---|---|---|---|
| BT1001 | Biology for Engineers | Core | 3 | Cell Structure and Function, Biomolecules, Genetics and Heredity, Microbial Diversity, Biological Processes |
| MA1001 | Engineering Mathematics-I | Core | 4 | Differential Calculus, Integral Calculus, Sequences and Series, Multivariable Calculus, Vector Calculus |
| PH1001 | Engineering Physics | Core | 4 | Wave Optics, Quantum Mechanics, Solid State Physics, Lasers and Fiber Optics, Electromagnetism |
| CH1001 | Engineering Chemistry | Core | 4 | Water Technology, Fuels and Combustion, Corrosion Science, Polymers and Composites, Electrochemistry |
| ME1001 | Engineering Drawing | Core | 2 | Orthographic Projections, Sectional Views, Isometric Projections, Perspective Views, CAD Introduction |
| HS1001 | English Communication Skills | Core | 2 | Listening Comprehension, Spoken English, Reading Strategies, Business Writing, Presentation Skills |
| ME1002 | Workshop Practice | Lab | 2 | Carpentry, Fitting, Welding, Machining Operations, Sheet Metal Work |
| BT1091 | Biology Lab | Lab | 1 | Microscopy Techniques, Cell Staining and Counting, Biochemical Tests, DNA Isolation, Enzyme Activity Assays |
Semester 2
| Subject Code | Subject Name | Subject Type | Credits | Key Topics |
|---|---|---|---|---|
| BT1002 | Introduction to Biotechnology | Core | 3 | History and Scope of Biotechnology, Genetic Engineering Principles, Industrial Applications, Medical Biotechnology, Bioethics and Regulations |
| MA1002 | Engineering Mathematics-II | Core | 4 | Linear Algebra, Ordinary Differential Equations, Partial Differential Equations, Fourier Series, Laplace Transforms |
| EE1001 | Basic Electrical Engineering | Core | 3 | DC Circuits, AC Circuits, Transformers, Electrical Machines, Power Systems Basics |
| EC1001 | Basic Electronics Engineering | Core | 3 | Semiconductor Diodes, Transistors, Rectifiers and Filters, Operational Amplifiers, Digital Logic Gates |
| CS1001 | Programming for Problem Solving | Core | 3 | C Programming Fundamentals, Control Flow Statements, Functions and Recursion, Arrays and Pointers, Structures and File Handling |
| CH1091 | Engineering Chemistry Lab | Lab | 1 | Volumetric Analysis, Water Quality Testing, Instrumental Methods, Polymer Synthesis, Corrosion Rate Measurement |
| PH1091 | Engineering Physics Lab | Lab | 1 | Optical Experiments, Semiconductor Characteristics, Magnetic Field Measurements, Resonance Phenomena, Ultrasonics |
| CS1091 | Programming for Problem Solving Lab | Lab | 1 | C Program Implementation, Debugging Techniques, Algorithmic Problem Solving, Data Structure Basics, Practical Coding Exercises |
| EE1091 | Basic Electrical Engineering Lab | Lab | 1 | Ohm''''s Law Verification, Circuit Analysis, Transformer Testing, Motor Characteristics, Power Measurement |
| EC1091 | Basic Electronics Engineering Lab | Lab | 1 | Diode and Transistor Characteristics, Rectifier Circuits, Amplifier Design, Oscillators, Digital Logic Gates Implementation |
Semester 3
| Subject Code | Subject Name | Subject Type | Credits | Key Topics |
|---|---|---|---|---|
| BT2001 | Biochemistry | Core | 3 | Biomolecules Structure and Function, Metabolism Pathways (Carbohydrate, Lipid, Protein), Enzyme Kinetics and Regulation, Bioenergetics, Molecular Pathways and Regulatory Mechanisms |
| BT2002 | Microbiology | Core | 3 | Microbial Diversity and Classification, Bacterial Growth and Nutrition, Control of Microorganisms, Virology and Mycology, Applied Microbiology |
| BT2003 | Fluid Mechanics & Heat Transfer | Core | 3 | Fluid Properties and Statics, Fluid Dynamics and Flow Regimes, Dimensional Analysis, Heat Transfer Mechanisms, Heat Exchangers |
| BT2004 | Cell Biology & Genetics | Core | 3 | Eukaryotic Cell Structure, Cell Cycle and Division, Mendelian Genetics, Chromosome Structure, Gene Expression and Regulation |
| MA2001 | Engineering Mathematics-III | Core | 4 | Probability and Statistics, Complex Variables, Integral Transforms, Numerical Methods, Optimization Techniques |
| BT2091 | Biochemistry Lab | Lab | 1 | Carbohydrate and Protein Estimation, Enzyme Kinetics Studies, Lipid and Nucleic Acid Analysis, Chromatographic Techniques, Spectrophotometric Methods |
| BT2092 | Microbiology Lab | Lab | 1 | Sterilization Techniques, Microbial Culture Methods, Staining Techniques, Bacterial Identification, Antibiotic Sensitivity Testing |
| BT2093 | Fluid Mechanics & Heat Transfer Lab | Lab | 1 | Viscosity Measurement, Flow Through Pipes, Pump Characteristics, Heat Transfer Coefficients, Fluidization Studies |
| PR2001 | Biology Research Project I | Project | 4 | Literature Survey, Problem Identification, Experimental Design, Data Collection, Report Writing |
Semester 4
| Subject Code | Subject Name | Subject Type | Credits | Key Topics |
|---|---|---|---|---|
| BT2005 | Molecular Biology | Core | 3 | DNA Replication and Repair, Transcription and RNA Processing, Translation and Protein Synthesis, Gene Regulation Mechanisms, Recombinant DNA Technology |
| BT2006 | Bioprocess Engineering | Core | 3 | Microbial and Enzyme Kinetics, Bioreactor Design and Operation, Sterilization of Bioreactors, Mass and Heat Transfer in Bioreactors, Fermentation Technology |
| BT2007 | Chemical Engineering Thermodynamics | Core | 3 | Laws of Thermodynamics, Thermodynamic Properties of Fluids, Phase Equilibria, Chemical Reaction Equilibria, Energy Balances in Processes |
| BT2008 | Immunology | Core | 3 | Components of Immune System, Antigens and Antibodies, Cellular and Humoral Immunity, Immunological Disorders, Immunodiagnostics |
| EN2001 | Environmental Science & Engineering | Core | 3 | Ecology and Ecosystems, Environmental Pollution, Waste Management, Environmental Impact Assessment, Sustainable Development |
| BT2094 | Molecular Biology Lab | Lab | 1 | DNA/RNA Isolation, PCR and RT-PCR, Gel Electrophoresis, Restriction Digestion, Bacterial Transformation |
| BT2095 | Bioprocess Engineering Lab | Lab | 1 | Fermenter Operation, Batch and Fed-Batch Culture, Biomass and Product Estimation, Downstream Processing Basics, Kinetic Studies |
| BT2096 | Immunology Lab | Lab | 1 | Blood Grouping, ELISA Technique, Agglutination Tests, Lymphocyte Isolation, Immunoblotting |
| PR2002 | Biology Research Project II | Project | 4 | Experimental Execution, Data Analysis and Interpretation, Scientific Presentation, Troubleshooting Experimental Issues, Mid-term Project Report |
Semester 5
| Subject Code | Subject Name | Subject Type | Credits | Key Topics |
|---|---|---|---|---|
| BT3001 | Genetic Engineering | Core | 3 | Gene Cloning Strategies, Expression Vectors, Gene Editing Technologies (CRISPR), Transgenic Animals and Plants, Ethical and Safety Aspects |
| BT3002 | Industrial Biotechnology | Core | 3 | Microbial Production of Metabolites, Enzyme Technology in Industry, Food and Pharmaceutical Biotechnology, Bioremediation, Biofuel Production |
| BT3003 | Bioseparation Technology | Core | 3 | Cell Disruption Methods, Filtration and Centrifugation, Chromatographic Separations, Electrophoretic Techniques, Membrane Separations |
| BT3004 | Bioinformatics | Core | 3 | Biological Databases, Sequence Alignment Algorithms, Phylogenetic Analysis, Protein Structure Prediction, Drug Discovery Approaches |
| HM3001 | Engineering Economics | Core | 3 | Basic Economic Principles, Market Structures, Cost Analysis, Project Evaluation Techniques, Financial Management |
| BT3091 | Genetic Engineering Lab | Lab | 1 | Recombinant Plasmid Construction, Bacterial Transformation, Gene Expression Analysis, Site-Directed Mutagenesis, CRISPR-Cas System Applications |
| BT3092 | Bioseparation Technology Lab | Lab | 1 | Dialysis and Ultrafiltration, Gel Filtration Chromatography, Ion Exchange Chromatography, Affinity Chromatography, Protein Precipitation Methods |
| BT3093 | Bioinformatics Lab | Lab | 1 | NCBI and UniProt Database Usage, BLAST and FASTA, Multiple Sequence Alignment Tools, Phylogenetic Tree Construction, Primer Design |
| PR3001 | Biology Research Project III | Project | 4 | Advanced Experimental Techniques, Data Interpretation, Statistical Analysis, Scientific Writing, Manuscript Preparation |
Semester 6
| Subject Code | Subject Name | Subject Type | Credits | Key Topics |
|---|---|---|---|---|
| BT3005 | Downstream Processing | Core | 3 | Cell Harvest and Lysis, Product Isolation, Initial Product Purification, High Resolution Purification, Formulation and Polishing |
| BT3006 | Animal Cell & Tissue Culture | Core | 3 | Animal Cell Culture Principles, Aseptic Techniques, Cell Line Maintenance, Primary Cultures and Cloning, Tissue Engineering and Regenerative Medicine |
| BT3007 | Plant Biotechnology | Core | 3 | Plant Tissue Culture Techniques, Plant Genetic Engineering, Crop Improvement Strategies, Secondary Metabolite Production, Molecular Breeding |
| HM3002 | Industrial Management | Core | 3 | Principles of Management, Production Planning and Control, Inventory Management, Quality Control, Human Resource Management |
| DE3xxx | Department Elective-I | Elective | 3 | Advanced Topics in Biotechnology, Specialized Biotechnological Applications, Emerging Biotechnologies, Interdisciplinary Bioprocesses, Biotechnology Entrepreneurship |
| BT3094 | Animal Cell Culture Lab | Lab | 1 | Cell Culture Media Preparation, Aseptic Handling, Cell Counting and Viability, Subculturing and Cryopreservation, Transfection Techniques |
| BT3095 | Plant Biotechnology Lab | Lab | 1 | Plant Tissue Culture Initiation, Callus Induction, Organogenesis and Micropropagation, Agrobacterium-mediated Transformation, Protoplast Isolation |
| PR3002 | Industrial Training / Project | Project | 4 | Industry Exposure, Practical Skill Development, Project Implementation, Professional Ethics, Teamwork and Communication |
| BT3096 | Downstream Processing Lab | Lab | 1 | Centrifugation and Filtration, Protein Precipitation, Chromatographic Purification, Ultrafiltration, Product Quality Analysis |
Semester 7
| Subject Code | Subject Name | Subject Type | Credits | Key Topics |
|---|---|---|---|---|
| OE4xxx | Open Elective-I | Elective | 3 | Interdisciplinary Skills Development, Non-Core Technical Subject, Management and Humanities, Emerging Technologies, Societal Impact of Technology |
| DE4xxx | Department Elective-II | Elective | 3 | Specialized Biotechnology Domain, Advanced Research Methodology, Specific Bioprocess Optimization, Bioinformatics Applications, Cellular and Molecular Therapies |
| DE4xxx | Department Elective-III | Elective | 3 | Advanced Biopharmaceutical Production, Environmental Bioremediation, Food Processing Technology, Biomaterials and Implants, Computational Biology |
| BT4001 | Bioprocess Control & Instrumentation | Core | 3 | Process Variables and Measurements, Sensors and Transducers, Control Strategies (PID), Data Acquisition Systems, Bioreactor Automation |
| BT4002 | Bioethics & IPR | Core | 3 | Ethical Issues in Biotechnology, Biosafety Guidelines, Intellectual Property Rights, Patents and Trademarks, Regulatory Frameworks |
| BT4091 | Bioprocess Control Lab | Lab | 1 | Sensor Calibration, Controller Tuning, pH and Temperature Control, Dissolved Oxygen Control, Data Logging and Analysis |
| PR4001 | B.Tech Project-I | Project | 4 | Project Planning and Scoping, In-depth Literature Review, Methodology Development, Preliminary Data Collection, Interim Report and Presentation |
Semester 8
| Subject Code | Subject Name | Subject Type | Credits | Key Topics |
|---|---|---|---|---|
| OE4xxx | Open Elective-II | Elective | 3 | Advanced Management Studies, Societal Challenges, Entrepreneurial Skills, Digital Technologies, Global Trends and Innovation |
| DE4xxx | Department Elective-IV | Elective | 3 | Bio-nanotechnology, Medical Devices and Diagnostics, Protein Engineering, Vaccine Technology, Agricultural Biotechnology |
| PR4002 | B.Tech Project-II | Project | 6 | Experimental Implementation, Advanced Data Analysis, Result Interpretation and Discussion, Thesis Writing and Documentation, Oral Defense and Presentation |
| BT4003 | Industrial Safety & Risk Management | Core | 3 | Hazard Identification and Assessment, Risk Mitigation Strategies, Safety Regulations and Standards, Emergency Preparedness, Accident Investigation |
| BT4004 | Regulatory Affairs & Quality Control | Core | 3 | Good Manufacturing Practices (GMP), Good Laboratory Practices (GLP), Quality Assurance Systems, Regulatory Agencies and Guidelines, Product Approval and Commercialization |
Semester 9
| Subject Code | Subject Name | Subject Type | Credits | Key Topics |
|---|---|---|---|---|
| BT5001 | Advanced Bioprocess Engineering | Core | 4 | Advanced Bioreactor Design, Bioprocess Scale-up and Optimization, Metabolic Engineering Principles, Process Modeling and Simulation, Biorefinery Concepts |
| BT5002 | Advanced Molecular Biology & Genetic Engineering | Core | 4 | Genomics and Proteomics, Transcriptomics and Metabolomics, Advanced Gene Editing Technologies, Recombinant Protein Production, Synthetic Biology |
| BT5101 | Enzyme Technology | Elective | 3 | Enzyme Production and Purification, Enzyme Kinetics and Mechanisms, Enzyme Immobilization, Applications of Enzymes in Industry, Enzyme Engineering |
| BT5102 | Biomaterial Science | Elective | 3 | Classes of Biomaterials, Properties of Biomaterials, Biocompatibility and Biointegration, Applications in Medical Devices, Tissue Engineering Scaffolds |
| BT5091 | Advanced Bioprocess Engg. Lab | Lab | 2 | Bioreactor Modeling Experiments, Fermentation Process Optimization, Advanced Bioprocess Analytics, Downstream Processing Optimization, Pilot Plant Operations |
| BT5092 | Advanced Mol. Bio. & Genetic Engg. Lab | Lab | 2 | Gene Expression Analysis Techniques, Protein Purification Strategies, Advanced DNA Manipulation, Cell Line Engineering, Omics Data Analysis |
| BT5093 | Seminar | Project | 2 | Scientific Literature Review, Critical Analysis of Research, Effective Presentation Skills, Oral Communication, Peer Feedback |
| PR5001 | Project Work I | Project | 2 | Research Problem Definition, In-depth Research Proposal, Experimental Design and Planning, Preliminary Data Collection, Progress Report |
Semester 10
| Subject Code | Subject Name | Subject Type | Credits | Key Topics |
|---|---|---|---|---|
| BT5103 | Pharmaceutical Biotechnology | Elective | 3 | Biopharmaceutical Production, Drug Discovery and Development, Vaccine Technology, Gene and Cell Therapy, Regulatory Aspects of Biologics |
| BT5104 | Environmental Biotechnology | Elective | 3 | Bioremediation of Pollutants, Waste Water Treatment, Solid Waste Management, Biofuel Production, Environmental Monitoring |
| PR5002 | Project Work II | Project | 16 | Comprehensive Experimental Execution, Advanced Data Interpretation, Thesis Writing and Manuscript Preparation, Research Publication, Viva-Voce Examination |
