

BACHELOR-OF-ENGINEERING in Biotechnology at Siddaganga Institute of Technology


Tumakuru, Karnataka
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About the Specialization
What is Biotechnology at Siddaganga Institute of Technology Tumakuru?
This Biotechnology program at Siddaganga Institute of Technology focuses on applying engineering principles to biological systems and living organisms, creating innovative products and solutions. With India''''s rapidly expanding biotech sector, particularly in pharmaceuticals, agriculture, and healthcare, this program is designed to meet the growing demand for skilled professionals who can bridge biology and technology. The curriculum emphasizes both theoretical knowledge and practical applications, preparing students for diverse roles in bio-industries.
Who Should Apply?
This program is ideal for aspiring engineers with a strong interest in biology, chemistry, and technology. It attracts fresh graduates eager to delve into cutting-edge fields like genetic engineering, bioprocess technology, and bioinformatics. Professionals seeking to upskill in specialized biotech domains or those looking to transition into the fast-evolving bio-economy in India will also find this program highly beneficial, provided they meet the scientific aptitude requirements.
Why Choose This Course?
Graduates of this program can expect promising career paths in India''''s leading pharmaceutical companies, biotech startups, research institutions, and food processing industries. Entry-level salaries typically range from INR 3-6 LPA, with significant growth potential up to INR 10-15+ LPA for experienced professionals. Career growth trajectories often include roles as Bioprocess Engineers, Research Scientists, Quality Control Analysts, Bioinformatics Specialists, and Regulatory Affairs associates, aligning with national and international industry certifications.

Student Success Practices
Foundation Stage
Master Fundamental Sciences with Application Focus- (Semester 1-2)
Dedicate significant effort to understanding core concepts in Physics, Chemistry, Mathematics, and basic Programming. Instead of rote learning, focus on how these principles are applied in engineering contexts, especially towards biological systems. Engage in problem-solving sessions and seek clarification on difficult topics promptly.
Tools & Resources
NPTEL courses for foundational subjects, Khan Academy, Reference textbooks beyond syllabus, Peer study groups
Career Connection
A strong foundation in these subjects is crucial for understanding complex biotechnology concepts and performing well in advanced courses, which directly impacts project selection and interview performance for core biotech roles.
Develop Early Programming Skills (Python/C)- (Semester 1-2)
Utilize the ''''Programming for Problem Solving'''' course to build strong logical thinking and coding skills. Practice extensively on online platforms and try to solve simple biological data problems or simulations using Python, even if basic. This creates a computational mindset essential for bioinformatics and data-driven biotech.
Tools & Resources
HackerRank, GeeksforGeeks, CodeChef, VS Code, Python documentation
Career Connection
Proficiency in programming opens doors to bioinformatics, computational biology, and data science roles within the biotech industry, significantly enhancing employability and research opportunities.
Engage in Interdisciplinary Project-Based Learning- (Semester 1-2)
Actively participate in the ''''Design Thinking & Innovation'''' course. Seek out opportunities to apply design thinking to small, real-world problems, perhaps related to campus waste management or energy efficiency. Collaborate with students from other branches to gain diverse perspectives and practice teamwork.
Tools & Resources
SIT Innovation Cell, Departmental project initiatives, Design Thinking workshops
Career Connection
Developing problem-solving and teamwork skills early on is vital for complex industry projects and collaborative research environments, making students more adaptable and valued by employers.
Intermediate Stage
Prioritize Hands-on Lab Experience and Documentation- (Semester 3-5)
Maximize learning from practical courses like Microbiology Lab, Genetic Engineering Lab, and Bioanalytical Techniques Lab. Focus on mastering experimental procedures, understanding the underlying principles, and meticulously documenting observations. Seek opportunities for extra lab time or assisting faculty in minor research work.
Tools & Resources
SIT Biotechnology labs, Department research projects, Lab notebooks, Scientific literature databases
Career Connection
Strong practical skills are non-negotiable for roles in R&D, Quality Control, and Bioprocess development. Excellent documentation is a key professional skill demanded by regulatory bodies in the biotech and pharma sector.
Seek Industry Exposure through Mini-Projects and Visits- (Semester 3-5)
Actively pursue the internship/mini-project opportunities. Connect with faculty mentors to identify local biotech or pharma companies for short-term projects or industrial visits. Even observing processes in a small startup can provide invaluable insight into real-world applications of theoretical knowledge.
Tools & Resources
SIT Placement Cell, Alumni network, LinkedIn for industry connections, Local industrial parks
Career Connection
Early industry exposure helps clarify career interests, builds a professional network, and provides practical context to academic learning, making students more ''''industry-ready'''' and attractive to recruiters.
Build a Foundational Network and Communication Skills- (Semester 3-5)
Attend seminars, workshops, and guest lectures by industry experts. Actively participate in student chapters of professional bodies (e.g., IGS, IEI). Practice technical communication by presenting ideas clearly and concisely, both written and verbally. Learn to articulate your project work effectively.
Tools & Resources
SIT departmental events, Technical clubs, Professional body student chapters, Toastmasters (if available)
Career Connection
Effective networking can lead to mentorship, internships, and job opportunities. Strong communication skills are crucial for technical discussions, presentations, and collaboration in any professional biotech setting.
Advanced Stage
Undertake a Comprehensive Research Project- (Semester 6-8)
Invest deeply in the semester-long Project Work (Phases I, II, III). Choose a topic aligned with your specialization interests and potential career path. Aim for impactful research, even if theoretical, focusing on problem-solving, experimental design, data analysis, and scientific writing.
Tools & Resources
SIT research labs, Faculty mentors, Statistical software (R, SPSS), Scientific journals (PubMed, Scopus)
Career Connection
A strong final year project is a powerful resume builder, showcasing your analytical, research, and problem-solving capabilities, essential for R&D roles, higher studies, and even startup ventures.
Target Strategic Internships and Industrial Training- (Semester 6-7)
Leverage the designated Internship period in 7th semester to gain significant industrial experience. Aim for internships at reputable biotech/pharma companies or leading research institutes. Focus on learning specific skills, understanding industrial workflows, and contributing meaningfully to projects.
Tools & Resources
SIT Placement Cell resources, Internship portals (Internshala, LinkedIn), Direct company applications
Career Connection
A well-executed internship often converts into a pre-placement offer (PPO) or provides crucial references and experience for securing jobs in top companies, accelerating your career growth.
Prepare for Placements and Higher Education Simultaneously- (Semester 7-8)
Begin placement preparation early by honing interview skills, mock interviews, aptitude tests, and resume building. Simultaneously, explore options for higher studies (M.Tech, MS) in specialized areas, preparing for GRE/GATE/TOEFL if applicable. Balance both paths to keep your options open.
Tools & Resources
SIT Training & Placement Department, Online aptitude platforms, Career counseling, University websites for higher studies
Career Connection
Being prepared for both immediate placements and higher education ensures you have clear pathways post-graduation, whether it''''s entering the industry in India or pursuing advanced research abroad or locally.
Program Structure and Curriculum
Eligibility:
- Candidates must have passed 2nd PUC / 12th standard or equivalent examination with English as one of the languages and obtained a minimum of 45% of marks (40% for SC/ST and Category-I) in aggregate in Physics and Mathematics along with Chemistry / Bio-Technology / Biology / Electronics / Computer Science / Information Technology / Technical Vocational subject. Admissions are through CET (KEA) or COMED-K.
Duration: 8 semesters / 4 years
Credits: 160 Credits
Assessment: Internal: 50%, External: 50%
Semester-wise Curriculum Table
Semester 1
| Subject Code | Subject Name | Subject Type | Credits | Key Topics |
|---|---|---|---|---|
| 23MAT11 | Calculus and Differential Equations | Core | 3 | Differential Calculus, Integral Calculus, Ordinary Differential Equations, Laplace Transforms, Multiple Integrals |
| 23PHY12 | Engineering Physics | Core | 3 | Quantum Mechanics, Solid State Physics, Lasers and Fiber Optics, Nanoscience and Technology, Wave Optics |
| 23ELE13 | Basic Electrical Engineering | Core | 3 | DC Circuits, AC Circuits, Three-Phase Systems, Transformers, Electrical Machines |
| 23CIV14 | Elements of Civil Engineering | Core | 3 | Surveying, Building Materials, Concrete Technology, Environmental Engineering, Water Resources Engineering |
| 23EGH15 | Professional English | Core | 2 | Communication Skills, Technical Writing, Presentation Skills, Reading Comprehension, Grammar and Vocabulary |
| 23PHYL16 | Engineering Physics Lab | Lab | 1 | Laser Wavelength, Optical Fiber N.A., Bandgap Determination, Frequency Response of RC Circuit, Dielectric Constant Measurement |
| 23EGH17 | Professional English Lab | Lab | 1 | Public Speaking, Group Discussions, Resume Writing, Interview Skills, Report Writing Practice |
| 23IDT18 | Design Thinking & Innovation | Core | 1 | Introduction to Design Thinking, Empathy and Problem Definition, Ideation Techniques, Prototyping and Testing, Innovation Strategies |
Semester 2
| Subject Code | Subject Name | Subject Type | Credits | Key Topics |
|---|---|---|---|---|
| 23MAT21 | Linear Algebra and Differential Equations | Core | 3 | Matrices and Determinants, Vector Spaces, Linear Transformations, Eigenvalues and Eigenvectors, Numerical Methods |
| 23CHE22 | Engineering Chemistry | Core | 3 | Electrochemistry, Corrosion and Its Control, Water Technology, Polymer Chemistry, Fuel Cells |
| 23CSE23 | Programming for Problem Solving | Core | 3 | C Programming Fundamentals, Data Types and Operators, Control Flow Statements, Functions and Arrays, Pointers and Structures |
| 23MECH24 | Elements of Mechanical Engineering | Core | 3 | Thermodynamics, IC Engines, Refrigeration and Air Conditioning, Power Transmission, Manufacturing Processes |
| 23EGR25 | Engineering Graphics | Core | 2 | Orthographic Projections, Isometric Projections, Sectional Views, Development of Surfaces, AutoCAD Basics |
| 23CHEL26 | Engineering Chemistry Lab | Lab | 1 | Water Quality Analysis, Titrimetric Analysis, Instrumental Analysis, Synthesis of Polymers, Corrosion Rate Determination |
| 23CSEL27 | Programming for Problem Solving Lab | Lab | 1 | C Programming Exercises, Conditional Statements, Looping Constructs, Function Implementation, Debugging Techniques |
| 23UHV28 | Universal Human Values | Core | 1 | Self-Exploration, Understanding Harmony in Human Relationships, Understanding Harmony in Society, Understanding Harmony in Nature, Ethical Human Conduct |
Semester 3
| Subject Code | Subject Name | Subject Type | Credits | Key Topics |
|---|---|---|---|---|
| 23BT31 | Applied Mathematics – III | Core | 3 | Fourier Series, Partial Differential Equations, Numerical Methods, Probability Distributions, Sampling Theory and Hypothesis Testing |
| 23BT32 | Biomolecules and Immunology | Core | 4 | Carbohydrates and Lipids, Proteins and Amino Acids, Nucleic Acids Structure and Function, Immune System Components, Antigen-Antibody Interactions |
| 23BT33 | Principles of Biochemical Engineering | Core | 4 | Enzyme Kinetics, Reactor Design Principles, Mass Transfer Operations, Heat Transfer Fundamentals, Fluid Mechanics in Bioprocesses |
| 23BT34 | Microbiology and Cell Biology | Core | 4 | Microbial Classification and Diversity, Bacterial Growth and Metabolism, Eukaryotic Cell Structure, Cell Cycle and Regulation, Cell Signaling Mechanisms |
| 23BT35 | Data Structures and Algorithms with Python | Core | 3 | Python Programming Basics, Linear Data Structures (Lists, Stacks, Queues), Non-Linear Data Structures (Trees, Graphs), Sorting and Searching Algorithms, Algorithm Analysis and Efficiency |
| 23BTL36 | Microbiology and Cell Biology Lab | Lab | 1 | Sterilization Techniques, Microbial Staining Methods, Bacterial Culture and Isolation, Microscopy Techniques, Cell Counting Methods |
| 23BTL37 | Data Structures and Algorithms with Python Lab | Lab | 1 | Python Programming Practice, Implementing Data Structures, Algorithm Implementation, Debugging Python Programs, Problem Solving through Coding |
| 23BT38 | Environmental Science and Engineering | Core | 0 | Ecosystems and Biodiversity, Environmental Pollution, Solid Waste Management, Environmental Impact Assessment, Sustainable Development |
Semester 4
| Subject Code | Subject Name | Subject Type | Credits | Key Topics |
|---|---|---|---|---|
| 23BT41 | Bioanalytical Techniques | Core | 4 | Spectroscopic Methods (UV-Vis, FTIR), Chromatographic Techniques (HPLC, GC), Electrophoresis (Agarose, SDS-PAGE), Microscopy (Light, Electron), Biosensors and Immunoassays |
| 23BT42 | Genetic Engineering | Core | 4 | DNA Replication and Repair, Gene Expression Regulation, Recombinant DNA Technology, Cloning Vectors and Enzymes, CRISPR-Cas9 Gene Editing |
| 23BT43 | Bioprocess Principles and Calculations | Core | 4 | Material Balances, Energy Balances, Stoichiometry of Microbial Growth, Sterilization Kinetics, Rheology of Bioprocess Fluids |
| 23BT44 | Human Physiology | Core | 3 | Organ Systems of the Human Body, Homeostasis and Feedback Mechanisms, Nervous System, Endocrine System, Cardiovascular and Respiratory Systems |
| 23BT45 | Chemical Engineering Thermodynamics | Core | 3 | Laws of Thermodynamics, Energy and Enthalpy Changes, Entropy and Free Energy, Phase Equilibria, Chemical Reaction Equilibria |
| 23BTL46 | Genetic Engineering Lab | Lab | 1 | DNA Isolation and Quantification, PCR Amplification, Agarose Gel Electrophoresis, Restriction Digestion, Bacterial Transformation |
| 23BTL47 | Bioanalytical Techniques Lab | Lab | 1 | Spectrophotometric Assays, Chromatography Techniques, Protein Electrophoresis, pH and Buffer Preparation, Enzyme Activity Assays |
| 23BT48 | Constitution of India and Professional Ethics | Core | 0 | Indian Constitution, Fundamental Rights and Duties, Professional Ethics in Engineering, Cyber Law, Intellectual Property Rights |
Semester 5
| Subject Code | Subject Name | Subject Type | Credits | Key Topics |
|---|---|---|---|---|
| 23BT51 | Downstream Processing | Core | 4 | Cell Disruption Methods, Solid-Liquid Separation (Filtration, Centrifugation), Membrane Separation Processes, Chromatographic Purification, Crystallization and Drying |
| 23BT52 | Bioreactor Design and Analysis | Core | 4 | Types of Bioreactors, Sterilization of Bioreactors, Aeration and Agitation, Bioreactor Mass and Energy Balances, Kinetics of Bioreactions |
| 23BT53 | Bioinformatics | Core | 3 | Biological Databases, Sequence Alignment (BLAST, FASTA), Phylogenetic Analysis, Proteomics and Genomics, Drug Discovery and Design |
| 23BTE54X | Professional Elective – I | Elective | 3 | Specialized topics in Food, Environmental, Plant, or Animal Biotechnology chosen by students. |
| 23BTE541 | Food Biotechnology | Elective | 3 | Fermented Foods, Food Additives, Food Safety, Genetic Modification in Food, Food Processing Technologies |
| 23BTE542 | Environmental Biotechnology | Elective | 3 | Bioremediation, Waste Treatment, Pollution Control, Biofuels, Environmental Monitoring |
| 23BTE543 | Plant Biotechnology | Elective | 3 | Plant Tissue Culture, Genetic Transformation of Plants, Crop Improvement, Molecular Breeding, Stress Tolerance in Plants |
| 23BTE544 | Animal Biotechnology | Elective | 3 | Animal Cell Culture, Transgenic Animals, Assisted Reproductive Technologies, Animal Health Diagnostics, Vaccine Production |
| 23BT55 | Enzyme Technology | Core | 3 | Enzyme Classification and Nomenclature, Enzyme Kinetics and Mechanisms, Enzyme Immobilization Techniques, Industrial Applications of Enzymes, Biosensors based on Enzymes |
| 23BTL56 | Downstream Processing Lab | Lab | 1 | Cell Disruption Techniques, Filtration and Centrifugation, Protein Precipitation, Chromatographic Separations, Drying Operations |
| 23BTL57 | Bioreactor Design and Analysis Lab | Lab | 1 | Batch Fermentation, Fed-Batch Fermentation, Sterilization Procedures, Kinetics of Microbial Growth, Oxygen Mass Transfer in Bioreactors |
| 23BT58 | Internship / Mini-Project | Project | 1 | Industry Exposure, Problem Identification, Literature Review, Project Execution, Report Writing |
Semester 6
| Subject Code | Subject Name | Subject Type | Credits | Key Topics |
|---|---|---|---|---|
| 23BT61 | Industrial Biotechnology | Core | 4 | Microbial Fermentation Processes, Production of Industrial Enzymes, Biofuels and Bioplastics, Secondary Metabolite Production, Biorefineries |
| 23BT62 | Genetic Engineering Applications | Core | 4 | Gene Therapy Approaches, Molecular Diagnostics, Production of Recombinant Proteins, Transgenic Organisms, Synthetic Biology Concepts |
| 23BTE63X | Professional Elective – II | Elective | 3 | Advanced specialized topics in Medical, Nano, Biopharmaceutical, or Food Process Technology. |
| 23BTE631 | Medical Biotechnology | Elective | 3 | Recombinant Therapeutics, Vaccine Development, Gene and Cell Therapy, Biomedical Diagnostics, Personalized Medicine |
| 23BTE632 | Nanobiotechnology | Elective | 3 | Nanomaterial Synthesis, Characterization Techniques, Nanomedicine, Biosensors, Drug Delivery Systems |
| 23BTE633 | Biopharmaceutical Technology | Elective | 3 | Biologics Production, Upstream Processing, Downstream Processing, Quality Control, Regulatory Affairs |
| 23BTE634 | Food Process Technology | Elective | 3 | Food Preservation, Unit Operations in Food Processing, Food Quality Control, Packaging Technology, Dairy and Meat Processing |
| 23BTS64X | Skill Enhancement Course – III | Skill Enhancement | 3 | Practical skills in Biostatistics and R Programming or Analytical Instrumentation. |
| 23BTS641 | Biostatistics and R Programming | Skill Enhancement | 3 | Descriptive Statistics, Inferential Statistics, Hypothesis Testing, R Programming for Data Analysis, Statistical Modeling |
| 23BTS642 | Analytical Instrumentation in Biotechnology | Skill Enhancement | 3 | Spectrophotometers, Chromatographs, Electrophoresis Systems, Microscopy Devices, Bioreactor Control Systems |
| 23BT65 | Research Methodology and IPR | Core | 3 | Research Problem Formulation, Literature Review, Research Design, Data Analysis and Interpretation, Intellectual Property Rights |
| 23BTL66 | Industrial Biotechnology Lab | Lab | 1 | Microbial Fermentation, Enzyme Production, Product Recovery, Quality Control, Biofuel Production |
| 23BTL67 | Genetic Engineering Applications Lab | Lab | 1 | Gene Cloning, Protein Expression, Western Blotting, ELISA, Cell-based Assays |
| 23BT68 | Research Project Phase – I | Project | 1 | Problem Identification, Literature Survey, Methodology Development, Project Proposal Writing, Initial Experimental Design |
Semester 7
| Subject Code | Subject Name | Subject Type | Credits | Key Topics |
|---|---|---|---|---|
| 23BTE71X | Professional Elective – III | Elective | 3 | Advanced topics in Tissue Engineering, Immunotechnology, Metabolic Engineering, or Agricultural Biotechnology. |
| 23BTE711 | Tissue Engineering and Regenerative Medicine | Elective | 3 | Biomaterials, Scaffold Design, Cell Culture for Tissue Engineering, Stem Cells, Organ Regeneration |
| 23BTE712 | Immunotechnology | Elective | 3 | Antibody Engineering, Immunodiagnostics, Vaccine Development, Flow Cytometry, Immunotherapy |
| 23BTE713 | Metabolic Engineering | Elective | 3 | Metabolic Pathways, Flux Analysis, Genetic Manipulation for Bioproduction, Systems Biology, Bioreactor Optimization |
| 23BTE714 | Agricultural Biotechnology | Elective | 3 | Crop Improvement, Pest and Disease Resistance, Biofertilizers, Biopesticides, Genetic Engineering in Agriculture |
| 23BTE72X | Professional Elective – IV | Elective | 3 | Specialized topics in Biosafety and Bioethics, Omics Technologies, Computational Biology, or Bioremediation. |
| 23BTE721 | Biosafety and Bioethics | Elective | 3 | Biosafety Levels, Risk Assessment, Ethical Principles, Intellectual Property in Biotech, Regulatory Guidelines |
| 23BTE722 | Omics Technologies | Elective | 3 | Genomics, Proteomics, Metabolomics, Transcriptomics, Next-Generation Sequencing |
| 23BTE723 | Computational Biology | Elective | 3 | Sequence Analysis, Protein Structure Prediction, Molecular Docking, Biological Network Analysis, Simulation Methods |
| 23BTE724 | Bioremediation | Elective | 3 | Microbial Degradation, Phytoremediation, Bioreactor Systems for Waste Treatment, Oil Spill Cleanup, Heavy Metal Detoxification |
| 23BTOE73X | Open Elective – A | Open Elective | 3 | General topics from other engineering disciplines or management, to broaden interdisciplinary knowledge. |
| 23BT74 | Project Work Phase – II | Project | 6 | Experimental Execution, Data Collection, Data Analysis, Interim Report Writing, Preliminary Results |
| 23BT75 | Internship | Internship | 1 | Industry Application of Knowledge, Professional Skill Development, Networking, Observation and Learning, Internship Report |
Semester 8
| Subject Code | Subject Name | Subject Type | Credits | Key Topics |
|---|---|---|---|---|
| 23BTE81X | Professional Elective – V | Elective | 3 | Industry-relevant advanced topics in Bioprocess Economics, Cell Culture, IP Management, or Environmental Health and Safety. |
| 23BTE811 | Bioprocess Economics and Plant Design | Elective | 3 | Process Economics, Feasibility Studies, Plant Layout Design, Scale-Up, Cost Analysis |
| 23BTE812 | Advanced Cell Culture Technology | Elective | 3 | Mammalian Cell Culture, Primary Cell Isolation, Stem Cell Culture, Cell Line Development, Troubleshooting Cell Culture |
| 23BTE813 | Intellectual Property Management in Biotechnology | Elective | 3 | Patent Law, Trademark and Copyright, Trade Secrets, Biotechnology Patenting, IP Strategy and Commercialization |
| 23BTE814 | Environmental Health and Safety | Elective | 3 | Industrial Safety, Hazard Identification, Risk Management, Environmental Regulations, Emergency Preparedness |
| 23BTOE82X | Open Elective – B | Open Elective | 3 | Further general topics from other engineering or management fields, for interdisciplinary learning. |
| 23BT83 | Project Work Phase – III | Project | 9 | Comprehensive Research, Advanced Experimentation, Data Interpretation, Thesis Writing, Project Defense |
| 23BT84 | Technical Seminar | Seminar | 1 | Current Research Trends, Literature Review, Presentation Skills, Critical Analysis, Technical Communication |
| 23BT85 | Technical Viva-Voce | Viva-Voce | 0 | Comprehensive assessment of engineering knowledge acquired throughout the program. |




