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B-TECH-M-TECH-INTEGRATED-DUAL-DEGREE in Pharmaceutical Engineering And Technology at Indian Institute of Technology (BHU) Varanasi

Indian Institute of Technology (BHU) Varanasi is a premier public technical university in Varanasi, Uttar Pradesh. Established in 1919 and gaining IIT status in 2012, it is renowned for academic excellence in engineering and interdisciplinary fields. Located on a sprawling 1300-acre campus, the institute offers diverse programs and achieves strong placements, ranking 10th in Engineering by NIRF 2024.

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Varanasi, Uttar Pradesh

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About the Specialization

What is Pharmaceutical Engineering and Technology at Indian Institute of Technology (BHU) Varanasi Varanasi?

This Pharmaceutical Engineering and Technology program at IIT (BHU) Varanasi focuses on applying engineering principles to the design, development, and manufacturing of pharmaceutical products. It uniquely integrates core engineering with pharmaceutical sciences, addressing the growing demand for skilled professionals in India''''s robust pharmaceutical industry. The program offers a blend of theoretical knowledge and practical applications relevant to modern drug production and healthcare innovations.

Who Should Apply?

This program is ideal for aspiring engineers and science graduates eager to contribute to the pharmaceutical sector. It suits fresh 10+2 graduates with a strong aptitude in PCM and those seeking a comprehensive understanding of drug development, manufacturing, and regulatory compliance. It also benefits individuals aiming for research and development roles, quality assurance, or process optimization in the rapidly expanding Indian pharma landscape.

Why Choose This Course?

Graduates of this program can expect diverse India-specific career paths in pharmaceutical manufacturing, R&D, quality control, and regulatory affairs. Entry-level salaries typically range from INR 6-10 lakhs per annum, with significant growth trajectories in major Indian pharmaceutical companies like Cipla, Dr. Reddy''''s, Sun Pharma, and Serum Institute. The program equips students with skills aligned with certifications like Six Sigma and GMP, enhancing their professional standing.

Student Success Practices

Foundation Stage

Strengthen Core Engineering & Science Fundamentals- (undefined)

Focus on building a strong foundation in Mathematics, Physics, Chemistry, and basic Computer Programming. Actively participate in labs and problem-solving sessions. Utilize online platforms like NPTEL for supplemental learning and practice past year JEE/GATE problems to reinforce concepts.

Tools & Resources

NPTEL courses for core subjects, Practice books for JEE/GATE foundation, Peer study groups, Departmental tutoring programs

Career Connection

A solid foundation in these subjects is crucial for understanding advanced pharmaceutical engineering concepts, which directly impacts performance in specialized courses and future problem-solving in industrial roles.

Develop Early Research and Communication Skills- (undefined)

Engage in small research projects under faculty guidance or join departmental clubs. Practice professional communication through presentations, technical writing, and group discussions from the very first year. Seek feedback to refine these essential soft skills.

Tools & Resources

University library resources for technical writing, Toastmasters International (if available), Departmental seminars and workshops, Faculty office hours

Career Connection

Strong communication and research skills are vital for technical reports, project proposals, and effectively collaborating in diverse teams in R&D and manufacturing, enhancing interview performance.

Explore Interdisciplinary Aspects- (undefined)

Actively attend introductory lectures or workshops on Pharmacy and Pharmaceutical Engineering. Understand how basic sciences connect with the specialized field. Read relevant articles and news about the Indian pharmaceutical industry to grasp real-world applications and challenges.

Tools & Resources

Departmental orientation sessions, Industry newsletters (e.g., Pharma Express), Online science magazines, Guest lectures by pharma professionals

Career Connection

This broad perspective helps in identifying potential areas of interest, making informed decisions about future specializations, and demonstrating a holistic understanding of the industry during internships and placements.

Intermediate Stage

Master Unit Operations and Analytical Techniques- (undefined)

Dive deep into subjects like Fluid Flow, Heat/Mass Transfer, and Pharmaceutical Analysis. Actively participate in labs, focusing on the practical application of theoretical concepts. Develop proficiency in using analytical instruments vital for drug development and quality control.

Tools & Resources

Lab manuals and standard operating procedures (SOPs), Simulation software for process operations, Online tutorials for analytical instruments, Textbooks on Unit Operations in Pharma

Career Connection

Proficiency in unit operations and analytical methods is highly sought after by pharmaceutical manufacturing and R&D companies, making graduates job-ready for roles in process engineering and quality assurance.

Seek Early Industry Exposure through Internships- (undefined)

Actively pursue summer internships (even short-term ones) at pharmaceutical companies, research labs, or related industries. This practical exposure helps in understanding industry workflows, applying academic knowledge, and building a professional network crucial for future placements.

Tools & Resources

University career services portal, LinkedIn and other professional networking platforms, Company websites for internship listings, Alumni network for guidance

Career Connection

Internships provide invaluable real-world experience, strengthen resumes, lead to potential pre-placement offers, and clarify career interests within the diverse pharmaceutical sector in India.

Engage in Departmental Electives and Projects- (undefined)

Carefully choose departmental electives that align with your career aspirations (e.g., Biopharmaceutics, Plant Design). Undertake mini-projects or term papers that allow you to apply learned concepts to specific pharmaceutical challenges, fostering problem-solving skills.

Tools & Resources

Faculty research areas and publications, Industry case studies, Academic journals (e.g., Indian Journal of Pharmaceutical Sciences), Departmental research labs

Career Connection

Specialized knowledge from electives makes you a stronger candidate for niche roles, while project experience showcases your ability to conduct independent work and contribute to technical advancements.

Advanced Stage

Focus on Regulatory Affairs and Quality Systems- (undefined)

Deepen your understanding of Quality Control, Quality Assurance, GMP, and regulatory affairs (e.g., ICH guidelines, Indian regulatory bodies like CDSCO). These are critical aspects of the pharmaceutical industry, especially in the context of global compliance and drug approvals in India.

Tools & Resources

Official websites of CDSCO, USFDA, EMA, Online courses on regulatory affairs, Industry whitepapers and standards, Guest lectures by regulatory experts

Career Connection

Expertise in regulatory and quality aspects is highly valued for roles in compliance, quality management, and product registration, ensuring adherence to strict Indian and international standards.

Undertake a Comprehensive Research Project (B.Tech & M.Tech)- (undefined)

Devote significant effort to your B.Tech and M.Tech research projects. Identify challenging problems, conduct thorough experiments, analyze data rigorously, and produce high-quality thesis/dissertation. Aim for publications or patent filings if the work is novel.

Tools & Resources

Faculty advisors and research groups, Advanced lab facilities and equipment, Statistical analysis software (e.g., SPSS, R), Scientific writing workshops

Career Connection

A strong research project is paramount for higher studies (PhD), R&D positions, and demonstrating advanced problem-solving, analytical, and innovation capabilities to top pharmaceutical companies and research institutions.

Prepare for Placements and Professional Development- (undefined)

Attend placement preparation workshops, practice aptitude tests, group discussions, and mock interviews. Tailor your resume and cover letters to specific job descriptions. Network extensively with alumni and industry professionals through conferences and seminars to explore diverse career opportunities in India''''s pharma sector.

Tools & Resources

University placement cell services, Online aptitude test platforms (e.g., IndiaBix), LinkedIn for professional networking, Industry conferences (e.g., PharmaTech)

Career Connection

Thorough placement preparation significantly increases chances of securing desirable job offers in leading pharmaceutical companies, contributing to a successful and impactful career start.

Program Structure and Curriculum

Eligibility:

  • No eligibility criteria specified

Duration: 10 semesters / 5 years

Credits: 200 Credits

Assessment: Assessment pattern not specified

Semester-wise Curriculum Table

Semester 1

Subject CodeSubject NameSubject TypeCreditsKey Topics
EAC-101Engineering GraphicsLab1.5Scales and Dimensions, Projection of Points and Lines, Projection of Planes, Projection of Solids, Section of Solids, Development of Surfaces
CHM-101ChemistryCore4Atomic Structure and Bonding, Thermodynamics and Electrochemistry, Kinetics and Catalysis, Polymers and Nanomaterials, Spectroscopy
CHM-102Chemistry LaboratoryLab1.5Volumetric Analysis, Gravimetric Analysis, Conductometry, Potentiometry, Colorimetry, Synthesis of Organic Compounds
CST-101Computer ProgrammingCore3Introduction to Programming, Data Types and Operators, Control Flow Statements, Functions and Arrays, Pointers and Structures, File Handling
CST-102Computer Programming LabLab1.5Basic C Programming, Conditional Statements and Loops, Array and String Manipulation, Functions and Recursion, Structure and Union, File Operations
MTH-101Mathematics – ICore4Differential Calculus, Integral Calculus, Multivariable Calculus, Sequences and Series, Matrices and Determinants
PHT-101Introduction to Pharmaceutical Engineering & TechnologyCore3Pharmaceutical Industry Overview, Drug Discovery and Development, Unit Operations in Pharma, Good Manufacturing Practices (GMP), Drug Delivery Systems, Career Opportunities
EAS-101Professional CommunicationCore2Communication Theory, Verbal and Non-verbal Communication, Technical Writing, Presentation Skills, Group Discussions, Interview Techniques

Semester 2

Subject CodeSubject NameSubject TypeCreditsKey Topics
EAC-102Workshop PracticeLab1.5Fitting Shop, Carpentry Shop, Welding Shop, Foundry Shop, Machine Shop, Sheet Metal Shop
EES-101Basic Electrical EngineeringCore4DC Circuits, AC Fundamentals, Transformers, DC Machines, AC Machines, Electrical Safety
EES-102Basic Electrical Engineering LabLab1.5Verification of Circuit Laws, Measurements in AC Circuits, Transformer Characteristics, DC Motor Speed Control, AC Motor Performance, Earthing and Safety
HSS-101Value Education & Human RightsHSS Core2Human Values and Ethics, Harmony in Society, Human Rights Principles, Constitutional Values, Professional Ethics, Sustainable Development
MTH-102Mathematics – IICore4Ordinary Differential Equations, Partial Differential Equations, Laplace Transforms, Fourier Series, Vector Calculus
PHY-101PhysicsCore4Classical Mechanics, Electromagnetism, Optics, Quantum Mechanics, Solid State Physics, Relativity
PHY-102Physics LaboratoryLab1.5Experimental Error Analysis, Optics Experiments, Electricity and Magnetism, Semiconductor Devices, Mechanical Properties, Thermal Properties
PHT-102Introduction to Pharmacy & Pharmaceutical SciencesCore3History of Pharmacy, Drug Nomenclature, Routes of Drug Administration, Dosage Forms, Pharmacopoeias, Ethical Pharmacy Practice

Semester 3

Subject CodeSubject NameSubject TypeCreditsKey Topics
CST-201Numerical MethodsCore3Solution of Algebraic Equations, Interpolation, Numerical Differentiation, Numerical Integration, Solution of ODEs, Curve Fitting
EAC-201Engineering MechanicsCore4Force Systems, Equilibrium, Friction, Kinematics of Particles, Kinetics of Particles, Work and Energy
MTH-201Mathematics – IIICore4Complex Analysis, Probability Theory, Random Variables, Probability Distributions, Sampling Theory, Statistical Inference
PHT-201Fluid Flow & Heat Transfer OperationsCore3Fluid Statics and Dynamics, Flow through Pipes, Pumps and Flow Meters, Heat Conduction, Heat Convection, Heat Exchangers
PHT-202Fluid Flow & Heat Transfer LabLab1.5Venturimeter and Orifice Meter, Friction Factor in Pipes, Pump Performance, Thermal Conductivity, Convection Heat Transfer, Heat Exchanger Performance
PHT-203Pharmaceutical Organic Chemistry ICore3Stereochemistry, Reaction Mechanisms, Nomenclature of Organic Compounds, Alkanes and Alkenes, Aromatic Compounds, Functional Group Chemistry
PHT-204Pharmaceutical Organic Chemistry I LabLab1.5Qualitative Analysis of Organic Compounds, Recrystallization and Distillation, Melting Point Determination, Synthesis of Simple Organic Molecules, Chromatographic Techniques, Spectroscopic Identification
PHT-205Engineering MaterialsCore3Atomic Structure and Bonding, Crystal Structures, Mechanical Properties of Materials, Polymers and Composites, Corrosion and its Control, Ceramics and Glasses

Semester 4

Subject CodeSubject NameSubject TypeCreditsKey Topics
EES-202Engineering ThermodynamicsCore4Laws of Thermodynamics, Thermodynamic Properties, Refrigeration Cycles, Power Cycles, Mixtures and Solutions, Chemical Equilibrium
PHT-206Mass Transfer OperationsCore3Diffusion and Mass Transfer Coefficients, Gas-Liquid Operations (Distillation), Liquid-Liquid Extraction, Drying and Evaporation, Crystallization, Adsorption and Ion Exchange
PHT-207Mass Transfer Operations LabLab1.5Binary Distillation, Liquid-Liquid Extraction, Tray Dryer Operation, Crystallization, Adsorption Column, Diffusion Coefficient Measurement
PHT-208Pharmaceutical Organic Chemistry IICore3Heterocyclic Compounds, Amino Acids and Proteins, Carbohydrates, Lipids, Medicinal Chemistry Principles, Drug-receptor Interactions
PHT-209Pharmaceutical Inorganic ChemistryCore3Purity of Inorganic Drugs, Impurities in Pharmaceuticals, Gastrointestinal Agents, Electrolytes, Topical Agents, Antacids and Laxatives
PHT-210Pharmaceutical Inorganic Chemistry LabLab1.5Qualitative Analysis of Inorganic Salts, Quantitative Analysis of Metal Ions, Limit Tests for Impurities, Assay of Inorganic Drugs, Preparation of Inorganic Pharmaceuticals, Complexometric Titrations
PHT-211Pharmaceutical Analysis ICore3Principles of Analysis, Acid-Base Titrations, Redox Titrations, Gravimetric Analysis, Potentiometry, Conductometry
PHT-212Pharmaceutical Analysis I LabLab1.5Preparation of Standard Solutions, Acid-Base Titration Exercises, Redox Titrations, Precipitation Titrations, Conductometric Titrations, Potentiometric Titrations

Semester 5

Subject CodeSubject NameSubject TypeCreditsKey Topics
HSS-301EconomicsHSS Elective3Microeconomics Principles, Macroeconomics Principles, Demand and Supply Analysis, Market Structures, National Income, Fiscal and Monetary Policies
PHT-301BiochemistryCore3Biomolecules (Proteins, Lipids, Carbohydrates), Enzymes and Coenzymes, Metabolic Pathways (Glycolysis, TCA Cycle), Bioenergetics, Nucleic Acids and Genetic Information, Vitamins and Hormones
PHT-302Biochemistry LabLab1.5Qualitative Tests for Biomolecules, Enzyme Activity Assays, Chromatographic Separation, Spectrophotometric Analysis, pH and Buffer Preparation, Protein Estimation
PHT-303Engineering Properties of Biological MaterialsCore3Physical and Mechanical Properties, Rheology of Biological Fluids, Thermal Properties, Electrical Properties, Mass Transfer Properties, Physicochemical Properties of Drugs
PHT-304Unit Operations in Pharmaceutical IndustryCore3Size Reduction and Separation, Mixing and Homogenization, Filtration and Centrifugation, Evaporation and Drying, Compaction and Compression, Sterilization Techniques
PHT-305Pharmaceutical Analysis IICore3UV-Visible Spectroscopy, Infrared Spectroscopy, Nuclear Magnetic Resonance (NMR), Mass Spectrometry, Chromatography (HPLC, GC), Electrophoresis
PHT-306Pharmaceutical Analysis II LabLab1.5UV-Visible Spectrophotometry, IR Spectroscopy Analysis, Chromatographic Separations (TLC, Column), High-Performance Liquid Chromatography (HPLC), Gas Chromatography (GC), Electrophoretic Techniques
PHT-307Basic BiotechnologyCore3Recombinant DNA Technology, Gene Cloning and Expression, Bioreactors and Fermentation, Monoclonal Antibodies, Tissue Culture, Biosensors
PHT-308Basic Biotechnology LabLab1.5DNA Isolation and Quantification, Agarose Gel Electrophoresis, PCR Techniques, Restriction Digestion, Bacterial Transformation, Enzyme Immobilization

Semester 6

Subject CodeSubject NameSubject TypeCreditsKey Topics
EVS-301Environmental Science & EngineeringCore3Ecology and Ecosystems, Environmental Pollution (Air, Water, Soil), Solid Waste Management, Water Treatment, Waste Water Treatment, Environmental Impact Assessment
PHT-309Physical PharmaceuticsCore3States of Matter, Solubility and Dissolution, Colloidal Dispersions, Rheology and Viscosity, Interfacial Phenomena, Drug Stability and Degradation
PHT-310Physical Pharmaceutics LabLab1.5Solubility Determination, Viscosity Measurements, Surface Tension, Emulsion and Suspension Stability, Particle Size Analysis, Drug Release Studies
PHT-311Pharmacology & ToxicologyCore3General Pharmacology Principles, Autonomic Nervous System Drugs, Cardiovascular Drugs, Antibiotics and Antivirals, Principles of Toxicology, Drug Toxicity Mechanisms
PHT-312Pharmaceutical Engineering DesignCore3Process Flow Diagrams, Piping and Instrumentation Diagrams, Equipment Design Principles, Scale-up Considerations, Plant Layout and Design, Safety in Design
PHT-313Pharmaceutical Engineering Design LabLab1.5Process Simulation Software, Designing Unit Operations Equipment, P&ID Drafting, Process Flow Diagram Creation, Cost Estimation for Equipment, Safety Analysis Reports
PHT-314Research MethodologyCore3Research Problem Formulation, Literature Review, Research Design, Data Collection Methods, Statistical Analysis, Report Writing
PHT-351Advanced Pharmaceutical AnalysisDepartmental Elective I3 hyphenated techniques (GC-MS, LC-MS), Capillary Electrophoresis, NMR Spectroscopy Applications, Atomic Absorption Spectroscopy, X-Ray Diffraction, Thermal Analysis

Semester 7

Subject CodeSubject NameSubject TypeCreditsKey Topics
PHT-401Pharmaceutical Process Control & InstrumentationCore3Control System Fundamentals, Process Variables and Sensors, Controllers (PID), Control Valves, Distributed Control Systems, Batch Process Control
PHT-402Pharmaceutical Process Control & Instrumentation LabLab1.5Temperature Control, Pressure Control, Flow Control, Level Control, PID Controller Tuning, PLC Programming
PHT-403Pharmaceutical MicrobiologyCore3Microbial Growth and Control, Sterilization and Disinfection, Antibiotics and Resistance, Preservation of Pharmaceutical Products, Bioburden Testing, Good Microbiological Practices
PHT-404Pharmaceutical Microbiology LabLab1.5Sterilization Techniques, Bacterial Culture Methods, Antibiotic Sensitivity Testing, Disinfectant Efficacy Testing, Microbial Limit Tests, Aseptic Techniques
PHT-405Intellectual Property Rights & EntrepreneurshipCore3Introduction to IPR, Patents, Trademarks, Copyrights, Geographical Indications, Trade Secrets, Startup Ecosystem in India, Business Plan Development
PHT-451Biopharmaceutical EngineeringDepartmental Elective II3Biologics Manufacturing, Cell Culture Technology, Protein Purification, Vaccine Production, Gene Therapy, Quality Control for Biopharmaceuticals
PHT-407Open ElectiveOpen Elective3Various topics from other engineering/science disciplines as per availability
PHT-408Project (B.Tech.)Project3Problem Identification, Literature Review, Methodology Design, Data Analysis, Report Writing, Presentation

Semester 8

Subject CodeSubject NameSubject TypeCreditsKey Topics
PHT-409Bioprocess EngineeringCore3Microbial Kinetics, Bioreactor Design, Sterilization of Fermentation Media, Aeration and Agitation, Downstream Processing, Enzyme Technology
PHT-410Bioprocess Engineering LabLab1.5Batch Fermentation, Fed-Batch Fermentation, Continuous Fermentation, Bioreactor Performance, Product Recovery, Enzyme Immobilization
PHT-411Pharmaceutical Industrial ManagementCore3Principles of Management, Human Resource Management, Financial Management, Marketing Management, Supply Chain Management, Project Management
PHT-412Quality Control & Quality AssuranceCore3Quality Management Systems, Good Laboratory Practices (GLP), Good Manufacturing Practices (GMP), Validation and Calibration, Statistical Quality Control, Auditing and Regulatory Inspections
PHT-454Pharmaceutical MarketingDepartmental Elective III3Marketing Mix for Pharmaceuticals, Market Research in Pharma, Product Life Cycle, Pricing Strategies, Distribution Channels, Sales Force Management
PHT-414Comprehensive VivaViva Voce2Overall understanding of Pharmaceutical Engineering curriculum
PHT-415Industrial Training/ProjectProject3Industrial Exposure, Practical Application of Knowledge, Problem Solving in Industry, Technical Report Writing, Professional Networking

Semester 9

Subject CodeSubject NameSubject TypeCreditsKey Topics
PHT-501Advanced Separation ProcessesCore (M.Tech)3Membrane Separations (Reverse Osmosis, Ultrafiltration), Chromatographic Separations (Preparative HPLC), Supercritical Fluid Extraction, Electrophoretic Separations, Adsorption and Ion Exchange Processes, Crystallization Principles
PHT-502Advanced Separation Processes LabLab (M.Tech)1.5Membrane Permeation Studies, Ion-Exchange Chromatography, Supercritical Fluid Extraction Demo, Preparative Chromatography, Electrophoretic Separation of Biomolecules, Crystallization Parameter Optimization
PHT-503Advanced Drug Delivery SystemsCore (M.Tech)3Controlled Release Drug Delivery, Targeted Drug Delivery, Nanocarriers for Drugs, Liposomes and Niosomes, Polymeric Drug Delivery Systems, Transdermal Drug Delivery
PHT-504Advanced Drug Delivery Systems LabLab (M.Tech)1.5Preparation of Liposomes, Formulation of Nanoparticles, In Vitro Drug Release Studies, Transdermal Patch Preparation, Characterization of Drug Delivery Systems, Stability Studies of Formulations
PHT-505Nanotechnology in Pharmaceutical SciencesCore (M.Tech)3Fundamentals of Nanomaterials, Synthesis of Nanoparticles, Characterization Techniques, Nanomedicine Applications, Nanodiagnostics, Regulatory Aspects of Nanopharmaceuticals
PHT-506Research Project – IProject (M.Tech)3In-depth Literature Review, Experimental Design, Data Collection and Analysis, Problem Solving, Interim Report Writing, Presentation Skills
PHT-551Computer Aided Drug DesignDepartmental Elective IV (M.Tech)3Molecular Docking, QSAR Studies, De Novo Design, Virtual Screening, Pharmacophore Modeling, Computational Chemistry Software

Semester 10

Subject CodeSubject NameSubject TypeCreditsKey Topics
PHT-508Design & Development of Dosage FormsCore (M.Tech)3Preformulation Studies, Formulation Design (Tablets, Capsules, Liquids), Aseptic Product Development, Sterile Products, Packaging Development, Quality by Design (QbD)
PHT-509Design & Development of Dosage Forms LabLab (M.Tech)1.5Tablet Manufacturing, Capsule Filling, Syrup and Suspension Preparation, Ointment and Cream Formulation, Sterility Testing, Dissolution Rate Studies
PHT-510Research Project – IIProject (M.Tech)6Advanced Experimental Work, Hypothesis Testing, Independent Research, Thesis Writing, Oral Defense, Publication Preparation
PHT-554Industrial PharmacyDepartmental Elective V (M.Tech)3Drug Manufacturing Processes, Facility Design and Layout, Scale-up and Technology Transfer, Validation Master Plan, Good Automated Manufacturing Practices (GAMP), Supply Chain Logistics
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