
B-TECH in Biotechnology at Indian Institute of Technology Roorkee


Haridwar, Uttarakhand
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About the Specialization
What is Biotechnology at Indian Institute of Technology Roorkee Haridwar?
This Biotechnology program at Indian Institute of Technology Roorkee focuses on integrating engineering principles with biological sciences. It aims to address complex challenges in healthcare, agriculture, and industry, contributing significantly to India''''s growing bioeconomy. The curriculum emphasizes a strong foundation in core biotechnology concepts and their practical applications, fostering innovation and research aptitude.
Who Should Apply?
This program is ideal for aspiring engineers and scientists with a keen interest in biology and its technological applications. It suits fresh graduates seeking entry into the biopharmaceutical, food processing, and environmental sectors, and those aiming for research and development roles. Students with a strong aptitude for interdisciplinary problem-solving and a desire to contribute to health and sustainable development will thrive.
Why Choose This Course?
Graduates of this program can expect diverse career paths in India, including roles as Bioprocess Engineers, Research Scientists, Bioinformatics Analysts, and Quality Control specialists. Entry-level salaries typically range from INR 6-10 LPA, with experienced professionals earning significantly more in leading biotech companies. The program also effectively prepares students for advanced studies and leadership roles in India''''s expanding biotech industry and academia.

Student Success Practices
Foundation Stage
Strengthen Core Science & Mathematics- (Semester 1-2)
Dedicate time to master fundamental physics, chemistry, mathematics, and introductory biotechnology concepts. Utilize resources like NPTEL lectures for deeper understanding and practice problems regularly from recommended textbooks.
Tools & Resources
NPTEL, Khan Academy, Textbooks for problem-solving
Career Connection
A strong foundation is crucial for all advanced biotechnology subjects, essential for competitive exams, and prepares for core engineering roles in the biotech industry.
Develop Programming Skills Early- (Semester 1-2)
Actively engage in computer programming labs and online coding challenges. Learning basics of Python or C is essential for bioinformatics and data analysis, which are integral to modern biotechnology research and applications.
Tools & Resources
HackerRank, GeeksforGeeks, Python/C programming tutorials
Career Connection
These skills are highly sought after for roles in bioinformatics, computational biology, and data-driven R&D departments within biotech firms in India.
Engage in Collaborative Learning- (Semester 1-2)
Form study groups with peers to discuss complex topics, share notes, and solve challenging problems together. Participate in departmental introductory workshops or seminars to broaden understanding and build connections.
Tools & Resources
College library group study rooms, Online collaboration tools, Departmental seminars
Career Connection
Enhances problem-solving, communication, and teamwork abilities, which are highly valued attributes in interdisciplinary biotech R&D teams and project environments.
Intermediate Stage
Seek Early Research Exposure- (Semester 3-5)
Approach professors for opportunities to work on minor research projects or assist in ongoing lab work. This provides invaluable hands-on experience in core biotech techniques and familiarizes students with research methodologies.
Tools & Resources
Departmental research labs, Faculty project listings, Summer undergraduate research programs
Career Connection
Builds a strong research profile crucial for pursuing higher studies (M.Tech/Ph.D.) and securing R&D positions in academic or industrial settings.
Participate in Biotech Competitions & Workshops- (Semester 3-5)
Join college-level or national biotechnology quizzes, case study competitions, or hackathons. Attend specialized workshops on molecular biology, bioprocess engineering, or bioinformatics tools to gain practical expertise.
Tools & Resources
iGEM, Institutional technical festivals, Industry-sponsored workshops
Career Connection
Develops practical skills, enhances problem-solving abilities, and provides networking opportunities, significantly improving employability and visibility.
Build a Strong LinkedIn Profile & Network- (Semester 4-5)
Start building a professional online presence by creating and regularly updating a LinkedIn profile. Connect with alumni and industry professionals, and attend webinars and virtual conferences to understand current industry trends.
Tools & Resources
LinkedIn, Virtual career fairs, Industry webinars
Career Connection
Facilitates internship opportunities, mentorship, and future job prospects, especially within the dynamic Indian biotech ecosystem and multinational corporations operating in India.
Advanced Stage
Pursue Relevant Internships- (Semester 6-7 (summer breaks), Semester 7 (Industrial Training))
Secure industrial internships in biopharmaceutical companies, research institutes, or biotech startups. Focus on applying theoretical knowledge to real-world projects and gaining hands-on experience with industry-standard practices.
Tools & Resources
College placement cell, NPTEL/SWAYAM internship portals, Company career pages
Career Connection
Provides invaluable industry experience, strengthens your resume, and often leads to pre-placement offers or preferential hiring in top biotech companies.
Undertake a Comprehensive Project- (Semester 7-8)
Engage deeply in the final year project (Project Stage I and II), choosing a topic aligned with your career interests. Focus on independent research, critical analysis, robust experimental design, and thorough thesis writing.
Tools & Resources
Departmental labs, Faculty guidance, Scientific databases (PubMed, Scopus)
Career Connection
Demonstrates expertise, research capability, and problem-solving skills, which are crucial for R&D roles, academic positions, and applications for higher education.
Develop Soft Skills & Interview Preparation- (Semester 7-8)
Attend workshops on presentation skills, technical communication, and participate in mock interviews. Work on improving aptitude and logical reasoning for placement tests and group discussions to hone overall professional readiness.
Tools & Resources
Career services, Online interview platforms (e.g., InterviewBit), Professional communication courses
Career Connection
Crucial for excelling in placement interviews and developing into a well-rounded professional capable of leading teams and communicating effectively within Indian biotech firms and beyond.
Program Structure and Curriculum
Eligibility:
- No eligibility criteria specified
Duration: 4 years / 8 semesters
Credits: 165 Credits
Assessment: Assessment pattern not specified
Semester-wise Curriculum Table
Semester 1
| Subject Code | Subject Name | Subject Type | Credits | Key Topics |
|---|---|---|---|---|
| ECL-101 | Engineering Graphics | Core | 2 | Introduction to Engineering Drawing, Orthographic Projections, Isometric Projections, Sectional Views, Intersection of Surfaces, Development of Surfaces |
| PHN-101 | Physics - I | Core | 4 | Vector calculus and electrostatics, Magnetostatics, Electromagnetic Induction, Maxwell’s equations and waves, Physical Optics, Lasers |
| CYN-101 | Chemistry - I | Core | 4 | Structure and bonding, Inorganic Chemistry, Organic Chemistry fundamentals, Spectroscopy principles, Chemical thermodynamics |
| CEN-101 | Mechanics | Core | 4 | Introduction to Statics, Equilibrium of Rigid Bodies, Friction, Kinematics of Particles, Kinetics of Particles, Work-Energy and Impulse-Momentum |
| CCN-101 | Computer Programming | Core | 4 | Introduction to C programming, Data types and operators, Control flow statements, Functions and arrays, Pointers and strings, Structures and file I/O |
| HUN-101 | English for Communication | Core | 2 | Grammar and vocabulary, Reading comprehension, Writing skills (essays, reports), Listening and speaking, Presentation skills |
| PHP-101 | Physics Lab | Lab | 1 | Experiments on optics, Electricity and magnetism, Mechanical properties of materials, Modern physics concepts |
| CYP-101 | Chemistry Lab | Lab | 1 | Titrimetric analysis, Organic qualitative analysis, Physical chemistry experiments, Inorganic quantitative analysis |
| CCP-101 | Computer Programming Lab | Lab | 1 | Programming exercises in C, Algorithm implementation, Debugging techniques, Data structure implementation basics |
| HUP-101 | Language Lab | Lab | 1 | Phonetics and pronunciation, Group discussions, Role-playing, Public speaking practice, Interview skills |
| SWC-101 | Sports, Games and NCC/NSS/NSO | Audit | P/F | Physical Fitness, Team Sports, Individual Sports, Community Service, Leadership Development |
Semester 2
| Subject Code | Subject Name | Subject Type | Credits | Key Topics |
|---|---|---|---|---|
| PHN-102 | Physics - II | Core | 4 | Quantum Mechanics, Atomic and Molecular Physics, Solid State Physics, Semiconductor Physics, Nuclear Physics |
| CYN-102 | Chemistry - II | Core | 4 | Chemical kinetics, Electrochemistry, Coordination Chemistry, Polymer Chemistry, Environmental Chemistry, Analytical techniques |
| MTN-101 | Mathematics - I | Core | 4 | Differential Calculus, Integral Calculus, Sequences and Series, Multivariable Calculus, Vector Calculus |
| EED-101 | Basic Electrical Technology | Core | 3 | DC Circuits, AC Circuits, Magnetic Circuits, Transformers, DC and AC Machines, Basic Electronics |
| ECN-101 | Electronics | Core | 3 | Semiconductor Diodes, Bipolar Junction Transistors (BJTs), Field-Effect Transistors (FETs), Operational Amplifiers, Digital Electronics Basics |
| BBN-101 | Introduction to Biotechnology | Core | 3 | History and scope of biotechnology, Genetic engineering principles, Industrial biotechnology, Medical biotechnology, Environmental and agricultural biotechnology |
| PHP-102 | Physics Lab | Lab | 1 | Experiments on quantum mechanics, Atomic spectroscopy, Solid state device characteristics, Semiconductor device applications |
| CYP-102 | Chemistry Lab | Lab | 1 | Electrochemistry experiments, Coordination compound synthesis, Polymer characterization, Analytical instrument usage |
| EET-101 | Basic Electrical Technology Lab | Lab | 1 | Experiments on DC/AC circuits, Verification of circuit laws, Measurement of electrical parameters, Transformer characteristics |
| SWC-102 | Sports, Games and NCC/NSS/NSO | Audit | P/F | Physical Fitness, Team Sports, Individual Sports, Community Service, Leadership Development |
Semester 3
| Subject Code | Subject Name | Subject Type | Credits | Key Topics |
|---|---|---|---|---|
| MTN-201 | Mathematics - II | Core | 4 | Linear Algebra (Matrices, Vectors), Differential Equations (First order, Higher order), Laplace Transforms, Fourier Series, Partial Differential Equations |
| BTN-201 | Cell Biology | Core | 3 | Cell structure and organelles, Cell division and cycle, Cell signaling, Membrane transport, Extracellular matrix and cell adhesion, Apoptosis |
| BTP-201 | Cell Biology Lab | Lab | 1 | Microscopy techniques, Cell staining, Cell counting, Cell viability assays, Cell culture basics |
| BTN-202 | Biochemistry | Core | 3 | Biomolecules (proteins, carbohydrates, lipids, nucleic acids), Amino acids and protein structure, Enzyme kinetics, Metabolism (glycolysis, TCA cycle), Bioenergetics |
| BTP-202 | Biochemistry Lab | Lab | 1 | Qualitative tests for biomolecules, Enzyme assays, Protein estimation, Spectrophotometry applications, Chromatography techniques |
| BTN-203 | Microbiology | Core | 3 | History of microbiology, Microbial classification and diversity, Microbial growth and nutrition, Sterilization and disinfection, Antimicrobial agents, Virology |
| BTP-203 | Microbiology Lab | Lab | 1 | Sterilization techniques, Microbial culturing, Staining methods, Microbial identification, Antibiotic sensitivity testing |
| HUC-201 | Environmental Studies | Core | 3 | Ecosystems and biodiversity, Environmental pollution, Natural resources, Climate change, Environmental management |
| HUE-0XX | Humanities Elective | Elective | 3 | Various topics in humanities, arts, social sciences as per chosen elective |
| OEC-01 | Open Elective | Elective | 3 | Topics from other engineering/science disciplines as per chosen elective |
Semester 4
| Subject Code | Subject Name | Subject Type | Credits | Key Topics |
|---|---|---|---|---|
| BTN-204 | Molecular Biology | Core | 3 | DNA replication, Transcription, Translation, Gene regulation (prokaryotic and eukaryotic), Mutations and DNA repair, Recombinant DNA technology |
| BTP-204 | Molecular Biology Lab | Lab | 1 | DNA extraction, Gel electrophoresis, PCR, Restriction digestion, Ligation, Transformation |
| BTN-205 | Biochemical Engineering | Core | 3 | Principles of mass and energy balance, Enzyme kinetics and reactor design, Microbial growth kinetics, Bioreactor operation, Downstream processing basics |
| BTP-205 | Biochemical Engineering Lab | Lab | 1 | Enzyme kinetics experiments, Batch bioreactor operation, Sterilization validation, Mixing in bioreactors |
| BTN-206 | Genetic Engineering | Core | 3 | Recombinant DNA tools, Gene cloning strategies, Gene expression systems, Site-directed mutagenesis, Transgenic organisms, Gene therapy |
| BTP-206 | Genetic Engineering Lab | Lab | 1 | Plasmid isolation, Gene cloning, Restriction mapping, Southern/Northern blotting, Western blotting |
| BTN-207 | Bioprocess Technology | Core | 3 | Bioreactor design and types, Sterilization of fermenters, Media formulation, Fermentation processes, Product recovery, Biosensors |
| BTN-208 | Biostatistics | Core | 3 | Introduction to statistics, Probability distributions, Hypothesis testing, ANOVA, Regression and correlation, Experimental design |
| HUE-0XX | Humanities Elective | Elective | 3 | Various topics in humanities, arts, social sciences as per chosen elective |
| OEC-02 | Open Elective | Elective | 3 | Topics from other engineering/science disciplines as per chosen elective |
Semester 5
| Subject Code | Subject Name | Subject Type | Credits | Key Topics |
|---|---|---|---|---|
| BTN-301 | Immunology | Core | 3 | Components of immune system, Innate and adaptive immunity, Antibody structure and function, T cell and B cell activation, Hypersensitivity, Autoimmunity |
| BTP-301 | Immunology Lab | Lab | 1 | Immunodiffusion, ELISA, Western blotting, Flow cytometry, Lymphocyte isolation, Antibody purification |
| BTN-302 | Enzyme Technology | Core | 3 | Enzyme structure and mechanism, Enzyme kinetics and inhibition, Enzyme immobilization, Industrial applications of enzymes, Enzyme purification |
| BTP-302 | Enzyme Technology Lab | Lab | 1 | Enzyme activity assay, pH and temperature effects, Enzyme immobilization techniques, Industrial enzyme characterization |
| BTN-303 | Downstream Processing | Core | 3 | Cell disruption, Solid-liquid separation, Filtration, Centrifugation, Chromatography, Crystallization, Drying |
| BTP-303 | Downstream Processing Lab | Lab | 1 | Cell disruption methods, Microfiltration, Ultrafiltration, Ion-exchange chromatography, Gel filtration chromatography |
| BTN-304 | Bioinformatics | Core | 3 | Sequence alignment, Database searching (BLAST), Phylogenetics, Protein structure prediction, Genomics databases, Drug discovery tools |
| BTP-304 | Bioinformatics Lab | Lab | 1 | Using bioinformatics tools, Sequence analysis, Protein modeling, Database queries, Primer design |
| BTD-XXX | Departmental Elective 1 | Elective | 3 | Selection from various specialized biotechnology topics, e.g., Systems Biology, Biomaterials, Genetic Engineering in Agriculture etc. |
| OEC-03 | Open Elective | Elective | 3 | Topics from other engineering/science disciplines as per chosen elective |
Semester 6
| Subject Code | Subject Name | Subject Type | Credits | Key Topics |
|---|---|---|---|---|
| BTN-305 | Genomics and Proteomics | Core | 3 | Genome sequencing methods, Functional genomics, Transcriptomics, Proteome analysis, Protein-protein interactions, Metabolomics |
| BTP-305 | Genomics and Proteomics Lab | Lab | 1 | DNA sequencing data analysis, Microarray data analysis, Proteomics data analysis (2D gel), Mass spectrometry basics |
| BTN-306 | Cell and Tissue Engineering | Core | 3 | Cell culture fundamentals, Scaffolds for tissue engineering, Bioreactors for tissue engineering, Stem cells, Regenerative medicine, Tissue specific applications |
| BTP-306 | Cell and Tissue Engineering Lab | Lab | 1 | Aseptic cell culture, Cell proliferation assays, Biocompatibility testing, Scaffold fabrication |
| BTN-307 | Nanobiotechnology | Core | 3 | Nanomaterials in biology, Nanoparticles for drug delivery, Nanosensors, Nanodiagnostics, Bionanomachines, Ethics of nanotechnology |
| BTD-XXX | Departmental Elective 2 | Elective | 3 | Selection from various specialized biotechnology topics, e.g., Environmental Biotechnology, Industrial Biotechnology, Structural Biology etc. |
| BTD-XXX | Departmental Elective 3 | Elective | 3 | Selection from various specialized biotechnology topics, e.g., Food Biotechnology, Animal Biotechnology, Plant Biotechnology etc. |
| OEC-04 | Open Elective | Elective | 3 | Topics from other engineering/science disciplines as per chosen elective |
| BTI-301 | Industrial Project | Project | P/F | Project planning, Industry problem solving, Data analysis, Report writing, Presentation skills |
Semester 7
| Subject Code | Subject Name | Subject Type | Credits | Key Topics |
|---|---|---|---|---|
| BTN-401 | Biosafety and Bioethics | Core | 3 | Biosafety levels, Risk assessment, Good laboratory practices, Ethical considerations in biotechnology, Intellectual property rights, Regulatory affairs |
| BTD-XXX | Departmental Elective 4 | Elective | 3 | Selection from various specialized biotechnology topics, e.g., Stem Cell and Regenerative Biology, Biosensors, Bioentrepreneurship etc. |
| BTD-XXX | Departmental Elective 5 | Elective | 3 | Selection from various specialized biotechnology topics, e.g., Biomedical Instrumentation, Biological Data Mining, Computational Biology etc. |
| OEC-05 | Open Elective | Elective | 3 | Topics from other engineering/science disciplines as per chosen elective |
| OEC-06 | Open Elective | Elective | 3 | Topics from other engineering/science disciplines as per chosen elective |
| BTP-401 | Project Stage - I | Project | 6 | Research methodology, Literature review, Experimental design, Data collection and analysis, Interim report writing |
| BTT-401 | Industrial Training | Training | P/F | Industry exposure, Practical skill development, Application of theoretical knowledge, Professional work ethics, Report generation |
Semester 8
| Subject Code | Subject Name | Subject Type | Credits | Key Topics |
|---|---|---|---|---|
| BTD-XXX | Departmental Elective 6 | Elective | 3 | Selection from various specialized biotechnology topics, e.g., Synthetic Biology, Metabolic Engineering, Biofuels and Biorefineries etc. |
| BTD-XXX | Departmental Elective 7 | Elective | 3 | Selection from various specialized biotechnology topics, e.g., Machine Learning in Biotechnology, Advanced Biostatistics, Clinical Biotechnology etc. |
| OEC-07 | Open Elective | Elective | 3 | Topics from other engineering/science disciplines as per chosen elective |
| BTP-402 | Project Stage - II | Project | 12 | Advanced research, Hypothesis testing, Comprehensive data analysis, Thesis writing, Oral presentation |




