

M-TECH-GENERAL in Computational Biology Cb at Indraprastha Institute of Information Technology Delhi


Delhi, Delhi
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About the Specialization
What is Computational Biology (CB) at Indraprastha Institute of Information Technology Delhi Delhi?
This Computational Biology (CB) program at IIIT Delhi focuses on the interdisciplinary application of computational techniques to solve complex biological problems. It addresses the growing need for professionals who can analyze vast biological datasets, crucial for advancements in Indian healthcare and biotechnology. The program distinguishes itself with a strong emphasis on machine learning, data analytics, and genomics, highly relevant to India''''s burgeoning biotech sector.
Who Should Apply?
This program is ideal for engineering or science graduates with a strong analytical aptitude seeking entry into the rapidly expanding field of bioinformatics and health informatics. It also suits working professionals from IT or life sciences backgrounds looking to upskill in data-driven biological research. Career changers transitioning into areas like drug discovery or personalized medicine will find the curriculum comprehensive.
Why Choose This Course?
Graduates of this program can expect diverse India-specific career paths, including roles as bioinformaticians, data scientists in pharma/biotech, computational biologists in research labs, and health data analysts. Entry-level salaries typically range from INR 6-10 LPA, with experienced professionals earning INR 15-30+ LPA. Growth trajectories include lead research positions, product development, and academic roles, often aligning with national certifications.

Student Success Practices
Foundation Stage
Master Core Programming and Data Structures for CB- (Semester 1-2)
Dedicate significant time to mastering Python/R programming and core data structures. Practice implementing algorithms relevant to biological data manipulation, such as sequence alignment or graph traversal for biological networks. Utilize online platforms for coding challenges and project-based learning.
Tools & Resources
Python, R, Jupyter Notebooks, GeeksforGeeks, Rosalind.info
Career Connection
Strong programming foundations are essential for almost all computational biology roles, ensuring you can efficiently handle and process large biological datasets, which is key for internships and entry-level positions.
Build a Strong Statistical and Mathematical Base- (Semester 1-2)
Focus on understanding the underlying statistical and mathematical concepts used in computational biology. Regularly solve problems involving probability, hypothesis testing, and linear algebra. Participate in study groups to discuss complex topics and clarify doubts.
Tools & Resources
Khan Academy, MIT OpenCourseWare for Statistics, NCERT Mathematics (Class 11-12 refreshers)
Career Connection
A solid quantitative background is crucial for interpreting experimental results, developing new algorithms, and making data-driven decisions, which are highly valued by research labs and biotech companies.
Engage in Early Research Exposure and Peer Learning- (Semester 1-2)
Actively seek opportunities to assist professors or senior students on ongoing research projects, even for small tasks. Form peer study groups to review course material, discuss research papers, and collaboratively solve problems, fostering a deeper understanding of CB concepts.
Tools & Resources
Departmental Research Seminars, Google Scholar, ResearchGate
Career Connection
Early research experience helps in identifying areas of interest for your M.Tech project and builds valuable connections. Peer learning enhances problem-solving skills and communication, beneficial for team-based industry roles.
Intermediate Stage
Undertake Mini-Projects and Kaggle Competitions- (Semester 3)
Apply theoretical knowledge by working on mini-projects using real biological datasets (e.g., from NCBI, EMBL). Participate in Kaggle or similar data science competitions with a biological focus to gain practical experience and showcase problem-solving skills.
Tools & Resources
Kaggle, GitHub, NCBI Gene Expression Omnibus (GEO), PDB
Career Connection
Practical projects demonstrate your ability to apply skills to real-world problems, making your resume stand out to recruiters for internships and full-time positions in data science and bioinformatics roles.
Network with Industry Professionals and Attend Workshops- (Semester 3)
Actively attend webinars, workshops, and conferences focused on computational biology, bioinformatics, and health informatics. Engage with speakers and industry professionals to build a professional network and stay updated on industry trends. Leverage LinkedIn for professional connections.
Tools & Resources
LinkedIn, Bioinformatics India events, NASSCOM events, IIIT Delhi industry seminars
Career Connection
Networking opens doors to internship and job opportunities, provides insights into career paths, and helps in understanding industry expectations for specialized roles in companies across India.
Specialize through Electives and Online Certifications- (Semester 3)
Strategically choose electives that align with your career interests (e.g., AI in healthcare, genomics, drug discovery). Supplement your coursework with relevant online certifications from platforms like Coursera or NPTEL in advanced topics to deepen your specialization.
Tools & Resources
Coursera, edX, NPTEL, Specific domain-focused certifications
Career Connection
Specialized knowledge makes you a more attractive candidate for niche roles. Certifications validate your expertise in specific tools or areas, enhancing your profile for targeted job applications in the Indian biotech sector.
Advanced Stage
Focus on M.Tech Project for Publication and Portfolio- (Semester 3-4)
Treat your M.Tech project as a flagship work. Aim for high-quality research that can lead to a publication in a reputable journal or conference. This project should form the cornerstone of your professional portfolio, showcasing your expertise.
Tools & Resources
IEEE Xplore, PubMed, arXiv, Overleaf for thesis writing
Career Connection
A strong M.Tech project with potential for publication significantly boosts your credentials for research-oriented roles, PhD applications, and showcases your ability to conduct independent, high-impact work.
Prepare Rigorously for Placements and Interviews- (Semester 4)
Begin placement preparation early by practicing aptitude, technical questions (data structures, algorithms, ML/stats for CB), and mock interviews. Tailor your resume and cover letter to specific company requirements, highlighting relevant projects and skills.
Tools & Resources
LeetCode, HackerRank, InterviewBit, IIIT Delhi Placement Cell resources
Career Connection
Thorough preparation ensures you are interview-ready for top companies in computational biology, data science, and IT sectors, leading to better placement opportunities and higher package offers.
Develop Soft Skills and Professional Communication- (Semester 4)
Actively participate in group discussions, presentations, and workshops to enhance your communication, teamwork, and leadership skills. These ''''soft skills'''' are as vital as technical expertise in the workplace, especially in collaborative research or industry settings.
Tools & Resources
Toastmasters International (if available), Presentation tools, Public speaking courses
Career Connection
Effective communication and teamwork are critical for success in any professional environment. These skills help you articulate your ideas, collaborate effectively, and advance into leadership roles within Indian companies.
Program Structure and Curriculum
Eligibility:
- B.Tech/B.E. in CS/IT/EC/EE/BT/B.Sc. (Engg.) or MCA or M.Sc. in CS/IT/BT/Bioinformatics/Mathematics/Statistics/Physics/Chemistry/Electronics/Computational Sciences with 65% marks or equivalent CGPA. A valid GATE score is not mandatory but preferred. Final year students are also eligible to apply.
Duration: 4 semesters / 2 years
Credits: Minimum 64 credits Credits
Assessment: Assessment pattern not specified
Semester-wise Curriculum Table
Semester 1
| Subject Code | Subject Name | Subject Type | Credits | Key Topics |
|---|---|---|---|---|
| CB501 | Algorithms in Computational Biology | Core | 4 | Sequence Alignment Algorithms, Genome Assembly, Phylogenetic Tree Reconstruction, RNA Secondary Structure Prediction, Haplotype Phasing, Motif Finding |
| CB502 | Machine Learning for Computational Biology | Core | 4 | Supervised Learning, Unsupervised Learning, Deep Learning Architectures, Support Vector Machines, Decision Trees and Random Forests, Applications in Biological Data |
| CB503 | Biological Data Analytics | Core | 4 | Data Visualization for Biological Data, Statistical Inference, Dimension Reduction Techniques, Clustering Methods, RNA-Seq Data Analysis, Single-Cell Omics Analysis |
| CB504 | Bioinformatics and Genomics | Core | 4 | Sequence Alignment and Databases, Hidden Markov Models, Genome Assembly and Annotation, RNA-seq Data Analysis, Proteomics and Mass Spectrometry, Comparative Genomics |
Semester 2
| Subject Code | Subject Name | Subject Type | Credits | Key Topics |
|---|---|---|---|---|
| CB505 | Systems Biology | Core | 4 | Gene Regulatory Networks, Protein Interaction Networks, Metabolic Networks Modeling, Kinetic Modeling and Simulation, Omics Data Integration, Pathway Analysis |
| CB506 | Data Structures and Programming for CB | Core | 4 | Fundamental Data Structures (Lists, Trees, Graphs), Algorithmic Complexity, Programming Paradigms (Python/R), Object-Oriented Programming, File Handling for Biological Data, Version Control Systems |
| CB507 | Statistical Methods in Computational Biology | Core | 4 | Probability Theory and Distributions, Hypothesis Testing and p-values, Linear and Logistic Regression, ANOVA and Non-parametric Tests, Bayesian Statistics, High-dimensional Data Analysis |
| CB508 | Research Methods in CB | Core | 4 | Scientific Writing and Communication, Experimental Design and Protocols, Literature Review Techniques, Grant Proposal Writing, Ethical Considerations in Research, Presentation Skills |
| Elective-1 | Example Elective: Advanced Machine Learning for CB | Elective | 4 | Advanced Neural Networks, Generative Models (GANs, VAEs), Reinforcement Learning, Causal Inference in Biology, Time Series Analysis in Omics, Explainable AI in Healthcare |
Semester 3
| Subject Code | Subject Name | Subject Type | Credits | Key Topics |
|---|---|---|---|---|
| Elective-2 | Example Elective: Computational Neuroscience | Elective | 4 | Neuronal Modeling, Neural Signal Processing, Brain Imaging Analysis, Connectomics, Computational Models of Cognition, Neurological Disorders |
| Elective-3 | Example Elective: Biomedical Image Analysis | Elective | 4 | Image Segmentation, Feature Extraction, Image Registration, Deep Learning for Medical Images, Histopathology Image Analysis, Radiology Image Processing |
| MTP501 | M.Tech Project - Part I | Project | 8 | Problem Definition and Literature Review, Methodology Development, Initial Data Collection and Analysis, Experimental Design, Mid-term Report Preparation, Ethical Considerations |
Semester 4
| Subject Code | Subject Name | Subject Type | Credits | Key Topics |
|---|---|---|---|---|
| Elective-4 | Example Elective: Drug Design and Discovery | Elective | 4 | Target Identification, Ligand-Based Drug Design, Structure-Based Drug Design, Molecular Docking, Virtual Screening, ADMET Prediction |
| Elective-5 | Example Elective: Deep Learning for Health Informatics | Elective | 4 | Convolutional Neural Networks, Recurrent Neural Networks, Transformer Models, Electronic Health Record Analysis, Clinical Text Mining, Predictive Analytics in Healthcare |
| MTP502 | M.Tech Project - Part II | Project | 12 | Advanced Data Analysis, Model Implementation and Validation, Result Interpretation and Discussion, Final Thesis Writing, Research Paper Publication, Oral Presentation and Defense |




