

B-E in Biotechnology Engineering at JSS Science and Technology University


Mysuru, Karnataka
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About the Specialization
What is Biotechnology Engineering at JSS Science and Technology University Mysuru?
This B.E. Biotechnology Engineering program at Sri Jayachamarajendra College of Engineering (under JSS STU) focuses on integrating principles of biology and engineering to develop innovative solutions across healthcare, agriculture, and industry. It emphasizes bioprocess engineering, genetic engineering, bioinformatics, and downstream processing, crucial for India''''s growing bio-economy and pharmaceutical sector. The program stands out by bridging scientific discovery with practical application, preparing students for real-world biotechnological challenges and fostering a deep understanding of bio-industrial processes.
Who Should Apply?
This program is ideal for fresh 10+2 graduates with a strong aptitude in science, particularly biology and mathematics, who are passionate about applying engineering principles to biological systems. It also suits individuals aspiring to contribute to India''''s burgeoning biotechnology sector, including those seeking entry into research, manufacturing, or R&D roles. The curriculum is designed for analytical thinkers eager to innovate in areas like drug development, sustainable agriculture, and environmental solutions, providing a robust foundation for future specialists.
Why Choose This Course?
Graduates of this program can expect diverse India-specific career paths in biopharmaceutical companies, food processing industries, environmental agencies, and academic research institutions. Entry-level salaries typically range from INR 3.5 to 6 lakhs annually, with experienced professionals earning significantly more. Growth trajectories include roles as Bioprocess Engineers, Research Scientists, Quality Control Specialists, and Bioinformatics Analysts. The program aligns with industry demands, equipping students with skills relevant for certifications in GMP, GLP, and advanced biotechnological techniques, enhancing their employability in both Indian and global markets.

Student Success Practices
Foundation Stage
Build Strong Engineering & Scientific Fundamentals- (Semester 1-2)
Focus intensely on core subjects like Engineering Mathematics, Physics, Chemistry, and basic programming. Participate in problem-solving sessions, clarify doubts promptly, and practice numerical problems regularly to strengthen your analytical foundation. This stage is crucial for mastering the interdisciplinary nature of Biotechnology.
Tools & Resources
NPTEL courses for foundational engineering subjects, Khan Academy for concept clarity, Peer study groups
Career Connection
A solid foundation is essential for understanding advanced biotech concepts and for cracking competitive exams and technical interviews in later stages.
Develop Essential Laboratory Skills Early- (Semester 1-2)
Actively engage in all basic science and biotechnology lab sessions. Pay close attention to aseptic techniques, instrumentation, and data recording. Seek opportunities to assist faculty or senior students in lab projects to gain early hands-on experience beyond the curriculum.
Tools & Resources
Lab manuals and protocols, YouTube tutorials for basic lab techniques, Departmental equipment training sessions
Career Connection
Proficiency in basic lab skills is a direct requirement for entry-level R&D and manufacturing roles in biotech industries, making you immediately employable.
Enhance Professional Communication & Ethics- (Semester 1-2)
Utilize the ''''Professional Communication & Ethics'''' course to improve written and oral communication skills. Participate in debates, presentations, and technical writing workshops. Understand ethical considerations in science and engineering, which are vital for responsible professional practice.
Tools & Resources
Toastmasters clubs (if available), Grammarly for writing improvement, Online courses on professional ethics
Career Connection
Effective communication is critical for collaborating in teams, presenting research findings, and excelling in interviews, while ethics ensure a trustworthy professional image.
Intermediate Stage
Master Core Biotechnology Concepts & Lab Techniques- (Semester 3-5)
Deep dive into subjects like Cell Biology, Genetics, Biochemistry, Microbiology, and Molecular Biology. Complement theoretical knowledge with extensive practical work in associated laboratories. Focus on understanding the ''''why'''' behind experiments and interpreting results critically.
Tools & Resources
Textbooks by Lehninger, Stryer, Lodish, Biotech journals and online databases, Advanced lab equipment training
Career Connection
Strong grasp of core concepts and specialized lab skills directly qualifies you for roles in R&D, diagnostics, and bioprocess development.
Explore Bioinformatics and Programming Applications- (Semester 3-5)
Engage with bioinformatics tools and databases to analyze biological data. Learn programming languages (e.g., Python, R) relevant to biological data analysis. Undertake small projects applying computational methods to biological problems.
Tools & Resources
NCBI, EMBL-EBI databases, Coursera/edX courses on Bioinformatics/Python for Biologists, Kaggle challenges
Career Connection
Bioinformatics skills are highly sought after for drug discovery, genomic analysis, and personalized medicine, opening avenues in pharmaceutical and IT sectors.
Seek Industry Exposure through Internships & Workshops- (Semester 3-5)
Actively look for short-term internships, industrial visits, and workshops during breaks. Gain exposure to actual industrial processes, equipment, and challenges in biotech companies. Network with industry professionals and faculty working on industry-sponsored projects.
Tools & Resources
Departmental placement cell, LinkedIn for networking, Industry association events (e.g., ABLE)
Career Connection
Internships provide practical experience, build professional networks, and often lead to pre-placement offers, accelerating your career launch.
Advanced Stage
Undertake Impactful Project Work & Research- (Semester 6-8)
Choose a relevant final year project or research topic that aligns with your career interests and current industry trends. Work diligently on your project, applying all learned concepts and techniques. Aim for publications or presentations at conferences.
Tools & Resources
Departmental research labs, Research funding opportunities, Mendeley/Zotero for literature management
Career Connection
A strong project demonstrates problem-solving abilities, research aptitude, and specialized skills, making you a strong candidate for R&D roles and higher studies.
Prepare for Placements and Higher Education- (Semester 6-8)
Begin placement preparation early by honing interview skills, soft skills, and technical knowledge. Attend career counseling sessions and mock interviews. For higher studies, prepare for GRE/GATE/TOFEL and identify suitable universities and research areas.
Tools & Resources
Placement cell resources, Online aptitude test platforms, GATE/GRE coaching centers, Study abroad consultants
Career Connection
Effective preparation ensures successful placements in desired companies or admission to prestigious universities for advanced degrees, fulfilling career aspirations.
Specialize and Build a Professional Portfolio- (Semester 6-8)
Select professional electives carefully based on your career goals, allowing for specialization in areas like biopharmaceuticals, food biotechnology, or environmental biotech. Create a portfolio showcasing your projects, internships, publications, and certifications to highlight your unique skills.
Tools & Resources
Industry reports, Career mentors, Online portfolio platforms (e.g., GitHub for bioinformatics)
Career Connection
Specialization makes you a valuable asset to specific industries, while a well-curated portfolio effectively communicates your capabilities to potential employers or academic institutions.
Program Structure and Curriculum
Eligibility:
- Passed 10+2 (or equivalent) with Physics and Mathematics as compulsory subjects, along with Chemistry/Biotechnology/Biology/Computer Science/Electronics as optional subjects. Must have English as one of the languages of study and obtained a minimum of 45% marks (40% for SC/ST/OBC categories) in the optional subjects in the qualifying examination.
Duration: 4 years / 8 semesters
Credits: 140 Credits
Assessment: Internal: 50%, External: 50%
Semester-wise Curriculum Table
Semester 1
| Subject Code | Subject Name | Subject Type | Credits | Key Topics |
|---|---|---|---|---|
| 1BY101 | Engineering Mathematics – I for B.E. Biotechnology | Core | 4 | Differential Calculus, Integral Calculus, Multivariable Calculus, Vector Calculus, Differential Equations |
| 1HS101 | Professional Communication & Ethics | Humanities & Social Science | 2 | Technical Communication, Oral Communication Skills, Written Communication, Professional Ethics in Engineering, Environmental Studies |
| 1PH101 | Engineering Physics | Basic Science | 3 | Modern Physics, Quantum Mechanics Principles, Solid State Physics, Lasers and their Applications, Optical Fibers and Communication |
| 1ES101 | Elements of Civil Engineering and Mechanics | Engineering Science | 3 | Introduction to Civil Engineering, Engineering Mechanics Fundamentals, Construction Materials, Basic Surveying, Environmental Engineering Principles |
| 1ES102 | Basic Electrical Engineering | Engineering Science | 3 | DC Circuits Analysis, AC Circuits Fundamentals, Electrical Machines Overview, Introduction to Power Systems, Electrical Safety Practices |
| 1PHL101 | Engineering Physics Laboratory | Lab | 1 | Basic Physics Experiments, Optical Phenomena Experiments, Electrical Circuit Measurements, Semiconductor Device Characteristics |
| 1ESL102 | Basic Electrical Engineering Laboratory | Lab | 1 | Verification of Circuit Laws, AC Circuit Analysis Experiments, Motor Characteristics Study, Electrical Measurement Techniques |
| 1BYL101 | Biotechnology Engineering Laboratory - I | Lab | 1 | Microscopy Techniques, Sterilization Methods, pH Measurement, Cell Counting Methods, Basic Biochemical Tests |
Semester 2
| Subject Code | Subject Name | Subject Type | Credits | Key Topics |
|---|---|---|---|---|
| 2BY201 | Engineering Mathematics – II for B.E. Biotechnology | Core | 4 | Linear Algebra, Laplace Transforms, Fourier Series, Probability and Statistics, Numerical Methods |
| 2CY201 | Engineering Chemistry | Basic Science | 3 | Electrochemistry Principles, Corrosion and its Control, Water Technology, Polymer Chemistry Basics, Instrumental Methods of Analysis |
| 2ES201 | Programming for Problem Solving | Engineering Science | 3 | C Programming Fundamentals, Data Types and Operators, Control Structures, Functions and Arrays, Pointers and Structures |
| 2ES202 | Engineering Graphics | Engineering Science | 3 | Orthographic Projections, Isometric Projections, Sections of Solids, Development of Surfaces, Introduction to CAD |
| 2HS201 | Constitution of India & Professional Ethics | Humanities & Social Science | 1 | Indian Constitution Framework, Fundamental Rights and Duties, Directive Principles of State Policy, Professional Ethics and Values, Introduction to Cyber Law |
| 2CYL201 | Engineering Chemistry Laboratory | Lab | 1 | Volumetric Analysis and Titrations, pH Measurements and Buffer Preparation, Water Quality Analysis, Instrumental Analysis Experiments |
| 2ESL201 | Programming for Problem Solving Laboratory | Lab | 1 | C Programming Exercises, Algorithmic Problem Solving using C, Debugging Techniques, Data Structure Implementation |
| 2ESL202 | Computer Aided Engineering Graphics Practice | Lab | 1 | CAD Software Usage, 2D Drafting and Drawing, Basic 3D Modeling, Assembly Drawing |
| 2BYL201 | Biotechnology Engineering Laboratory - II | Lab | 1 | Cell Culture Techniques, Microscopic Imaging, Electrophoresis Techniques, Chromatography Principles, Enzyme Assays |
Semester 3
| Subject Code | Subject Name | Subject Type | Credits | Key Topics |
|---|---|---|---|---|
| 3BY301 | Engineering Mathematics – III for B.E. Biotechnology | Core | 4 | Fourier and Z-Transforms, Partial Differential Equations, Complex Variables, Probability Distributions, Statistical Inference |
| 3BY302 | Cell Biology & Genetics | Professional Core | 3 | Cell Structure and Organelles, Cell Cycle and Division, Mendelian Genetics Principles, Gene Expression Regulation, Chromosome Structure and Aberrations |
| 3BY303 | Basic Biochemistry | Professional Core | 3 | Biomolecules (Carbohydrates, Lipids, Proteins), Nucleic Acids Structure, Metabolic Pathways Overview, Enzyme Kinetics and Mechanisms, Bioenergetics |
| 3BY304 | Microbiology | Professional Core | 3 | Microbial Classification and Diversity, Bacterial Growth Kinetics, Sterilization and Disinfection, Industrial Microbiology Applications, Introduction to Immunology |
| 3BY305 | Fluid Mechanics & Unit Operations | Professional Core | 3 | Fluid Properties and Statics, Fluid Flow Dynamics, Pumps and Pumping Systems, Filtration and Centrifugation, Mixing and Agitation |
| 3BYL301 | Cell Biology & Genetics Laboratory | Lab | 1 | Microscopy and Staining Techniques, Karyotyping, DNA Extraction, Gel Electrophoresis, Bacterial Staining Methods |
| 3BYL302 | Basic Biochemistry Laboratory | Lab | 1 | Qualitative Tests for Biomolecules, Enzyme Activity Assays, Spectrophotometry Applications, Chromatographic Separations |
| 3BYL303 | Microbiology Laboratory | Lab | 1 | Aseptic Techniques, Culture Media Preparation, Microbial Staining, Bacterial Growth Curve Analysis, Isolation of Microorganisms |
Semester 4
| Subject Code | Subject Name | Subject Type | Credits | Key Topics |
|---|---|---|---|---|
| 4BY401 | Engineering Mathematics – IV for B.E. Biotechnology | Core | 4 | Advanced Statistical Methods, Design of Experiments (DOE), Regression Analysis, Optimization Techniques, Reliability Engineering |
| 4BY402 | Molecular Biology | Professional Core | 3 | DNA Replication Mechanisms, Transcription Process, Translation Process, Gene Regulation, Mutagenesis and DNA Repair |
| 4BY403 | Bioprocess Principles & Calculations | Professional Core | 3 | Mass and Energy Balances, Stoichiometry in Bioprocesses, Bioreactor Design Fundamentals, Downstream Processing Introduction, Fermentation Kinetics |
| 4BY404 | Immunology | Professional Core | 3 | Immune System Components, Antigens and Antibodies, Hypersensitivity Reactions, Autoimmunity and Immunodeficiency, Immunodiagnostic Techniques |
| 4BY405 | Heat & Mass Transfer | Professional Core | 3 | Heat Conduction, Heat Convection and Radiation, Mass Diffusion, Mass Transfer Operations, Evaporation and Crystallization |
| 4BYL401 | Molecular Biology Laboratory | Lab | 1 | PCR Techniques, Restriction Digestion, Plasmid Isolation, Agarose Gel Electrophoresis, Blotting Techniques |
| 4BYL402 | Bioprocess Principles Laboratory | Lab | 1 | Fermentation Optimization, Product Recovery Methods, Mass Transfer Experiments, Sterilization Kinetics, Enzyme Reactor Studies |
| 4BYL403 | Immunology Laboratory | Lab | 1 | ELISA Technique, Agglutination Tests, Immunodiffusion, Blood Grouping, Western Blotting |
Semester 5
| Subject Code | Subject Name | Subject Type | Credits | Key Topics |
|---|---|---|---|---|
| 5BY501 | Genetic Engineering | Professional Core | 3 | Recombinant DNA Technology, Cloning Vectors, Gene Transfer Methods, PCR Applications, CRISPR-Cas9 Gene Editing |
| 5BY502 | Bioreactor Design & Analysis | Professional Core | 3 | Types of Bioreactors, Sterilization of Bioreactors, Mass Transfer in Bioreactors, Bioreaction Kinetics, Instrumentation and Control in Bioreactors |
| 5BY503 | Bioinformatics | Professional Core | 3 | Biological Databases, Sequence Alignment Algorithms, Phylogenetic Analysis, Proteomics and Genomics, Drug Design Principles |
| 5BYExx | Professional Elective – I (Choice of one from below) | Professional Elective | 3 | Food Biotechnology: Food Processing, Fermented Foods, Food Safety, Cancer Biology: Carcinogenesis, Oncogenes, Cancer Therapies, Environmental Biotechnology: Bioremediation, Biofuels, Waste Treatment, Nanobiotechnology: Nanomaterials, Nanomedicine, Biosensors |
| 5OExx | Open Elective – I (Various options across engineering disciplines) | Open Elective | 3 | Management Principles, Data Structures, Operations Research, Entrepreneurship, Material Science |
| 5BYL501 | Genetic Engineering Laboratory | Lab | 1 | Plasmid Transformation, Gene Cloning, Recombinant Protein Expression, PCR-based Cloning, Gene Construct Design |
| 5BYL502 | Bioreactor Design Laboratory | Lab | 1 | Bioreactor Operation, Sterilization Studies, Oxygen Transfer Rate Measurement, Microbial Growth Kinetics, Cell Immobilization Techniques |
| 5BYL503 | Bioinformatics Laboratory | Lab | 1 | Biological Database Querying, Sequence Alignment Tools (BLAST, ClustalW), Phylogenetic Analysis Software, Protein Structure Prediction, Virtual Screening for Drug Design |
Semester 6
| Subject Code | Subject Name | Subject Type | Credits | Key Topics |
|---|---|---|---|---|
| 6BY601 | Downstream Processing | Professional Core | 3 | Cell Disruption Methods, Solid-Liquid Separation (Filtration, Centrifugation), Chromatography Techniques, Crystallization and Drying, Product Polishing |
| 6BY602 | Animal & Plant Biotechnology | Professional Core | 3 | Animal Cell Culture, Transgenic Animals, Plant Tissue Culture, Transgenic Plants, Gene Editing in Eukaryotes |
| 6BY603 | Biostatistics & Research Methodology | Professional Core | 3 | Hypothesis Testing, ANOVA (Analysis of Variance), Correlation and Regression, Experimental Design, Scientific Writing and Presentation |
| 6BYExx | Professional Elective – II (Choice of one from below) | Professional Elective | 3 | Biofuels & Biorefineries: Bioethanol, Biodiesel, Biogas, Stem Cell & Regenerative Medicine: Stem Cell Types, Tissue Engineering, Gene Therapy, Pharmaceutical Biotechnology: Drug Discovery, Biopharmaceuticals, Vaccines, Food & Dairy Engineering: Food Processing, Dairy Technology, Quality Assurance |
| 6OExx | Open Elective – II (Various options across engineering disciplines) | Open Elective | 3 | Organizational Behavior, Intellectual Property Rights, Project Management, Renewable Energy Sources, Cyber Security |
| 6BYL601 | Downstream Processing Laboratory | Lab | 1 | Cell Lysis Methods, Protein Purification, Gel Filtration Chromatography, Ion Exchange Chromatography, Diafiltration |
| 6BYL602 | Animal & Plant Biotechnology Laboratory | Lab | 1 | Plant Tissue Culture Techniques, Callus Induction, Micropropagation, Animal Cell Culture, Cell Viability Assays |
| 6BY604 | Mini Project | Project | 1 | Problem Identification, Literature Survey, Experimental Design, Data Analysis, Technical Report Writing |
| 6BYINT01 | Internship / Industrial Training | Internship | 2 | Industry Exposure, Practical Skill Development, Project Work in Industry, Professional Networking, Internship Report Submission |
Semester 7
| Subject Code | Subject Name | Subject Type | Credits | Key Topics |
|---|---|---|---|---|
| 7BY701 | Professional Practice & Entrepreneurship | Professional Core | 3 | Intellectual Property Rights (IPR), Patents and Patenting Process, Bioethics and Regulatory Affairs, Project Management Principles, Business Plan Development |
| 7BYExx | Professional Elective – III (Choice of one from below) | Professional Elective | 3 | Enzyme Technology: Enzyme Kinetics, Immobilization, Industrial Enzymes, Biopharmaceutical Technology: Recombinant Proteins, Antibody Production, Gene Therapy, Food Process Engineering: Food Rheology, Preservation Technologies, Process Control, Biosensors & Bioinstrumentation: Biosensor Principles, Transducers, Clinical Diagnostics |
| 7BYExx | Professional Elective – IV (Choice of one from below) | Professional Elective | 3 | Medical Biotechnology: Diagnostics, Therapeutics, Regenerative Medicine, IPR & Biosafety: Patents, Trademarks, Biosafety Guidelines, Risk Assessment, Bioprocess Modelling & Simulation: Mathematical Models, Process Optimization, Simulation Software, Genetic Diagnostics: DNA Sequencing, Microarrays, PCR Diagnostics, Pharmacogenomics |
| 7OExx | Open Elective – III (Various options across engineering disciplines) | Open Elective | 3 | Supply Chain Management, Digital Marketing, Human Resource Management, Smart Materials, Artificial Intelligence Basics |
| 7BYL701 | Bioentrepreneurship & IPR Laboratory | Lab | 1 | Patent Search and Analysis, Business Plan Development, Market Analysis for Biotech Products, Regulatory Aspects of Biotech Startups, Case Studies in Biotech Entrepreneurship |
| 7BY702 | Project Work - Phase I | Project | 2 | Extensive Literature Review, Problem Definition and Scope, Methodology Design, Preliminary Results and Analysis, Interim Project Report |
Semester 8
| Subject Code | Subject Name | Subject Type | Credits | Key Topics |
|---|---|---|---|---|
| 8BY801 | Bioprocess Plant Design & Economics | Professional Core | 3 | Process Flow Diagrams, Equipment Sizing and Selection, Plant Layout and Utilities, Cost Estimation and Profitability Analysis, Economic Evaluation of Bioprocesses |
| 8BYExx | Professional Elective – V (Choice of one from below) | Professional Elective | 3 | Clinical Research & Trials: Drug Development, Clinical Trial Phases, GCP, Quality Control & Assurance in Bioprocess: GMP, GLP, Quality Systems, Validation, Biosafety & Risk Assessment: Biosafety Levels, Containment Strategies, Emergency Planning, Agri-Biotechnology: Crop Improvement, Plant Protection, Biofertilizers, Biopesticides |
| 8BY802 | Project Work - Phase II | Project | 5 | Experimental Work and Data Collection, Advanced Data Analysis and Interpretation, Result Discussion and Conclusion Formulation, Thesis Writing, Project Defense and Presentation |
| 8BY803 | Seminar | Seminar | 1 | In-depth Technical Literature Review, Preparation of Technical Presentation, Public Speaking and Communication Skills, Question and Answer Session Management, Critical Analysis of Current Research |




