Well-equipped Departmental and Research Laboratories | NIPER Kolkata offers well-equipped departmental and research laboratories that are fundamental to its academic and research endeavors. These state-of-the-art labs are furnished with the latest instruments, modern equipment, and advanced software, providing an ideal environment for hands-on learning and cutting-edge research in pharmaceutical sciences. They facilitate interdisciplinary access to sophisticated scientific tools, enabling students and faculty to conduct impactful experiments and innovations. | - Latest Instruments
- Modern Equipment
- Advanced Software
- Support For Teaching And Research Activities
- Interdisciplinary Access To Major Research Instruments
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Advanced Research Instruments (400 MHz NMR) | The 400 MHz NMR facility at NIPER Kolkata is a cornerstone of its advanced research capabilities, offering sophisticated analysis for molecular structure elucidation. This high-field instrument is crucial for various pharmaceutical and chemical research projects, providing detailed insights into compounds. It not only caters to the institute's internal research needs but also extends its services to external industries and research laboratories, fostering broader scientific collaboration. | - 400 Mhz Nuclear Magnetic Resonance (Nmr) Spectrometer
- Supports Complex Molecular Structure Determination
- Available For In-house And External Research
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Advanced Research Instruments (LC-MS QToF) | The LC-MS (QToF) system at NIPER Kolkata is a powerful analytical tool, enabling precise qualitative and quantitative analysis of complex samples. This instrument provides high-resolution mass measurements and detailed structural information, which is indispensable for drug discovery, metabolism studies, and impurity profiling in pharmaceutical research. Its advanced capabilities support rigorous scientific investigation and data generation for both academic and industrial applications. | - Liquid Chromatography-mass Spectrometry (Quadrupole Time-of-flight) System
- Provides Accurate Mass Measurements And Structural Information
- Used For Qualitative And Quantitative Analysis Of Compounds
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Advanced Research Instruments (HPLC & Preparative HPLC) | NIPER Kolkata's laboratories are equipped with both analytical and preparative HPLC systems, vital for the separation, identification, and purification of compounds. The analytical HPLC is used for precise quantitative and qualitative analysis, while the preparative HPLC enables the isolation of larger quantities of purified substances for further study or application. These instruments are fundamental to various research areas, including drug synthesis, natural product isolation, and quality control. | - High-performance Liquid Chromatography (Hplc) Systems
- Preparative Hplc For Compound Purification
- Essential For Separation And Analysis Of Chemical Mixtures
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Advanced Research Instruments (CD Spectrophotometer) | The CD Spectrophotometer at NIPER Kolkata is a specialized instrument used to analyze the secondary structure and conformational changes of biomolecules, particularly proteins and peptides. This facility is invaluable for research in structural biology, drug design, and understanding molecular interactions. It provides critical data for characterizing the folding and stability of potential therapeutic agents, advancing pharmaceutical development. | - Circular Dichroism (Cd) Spectrophotometer
- Analyzes The Secondary Structure Of Proteins And Other Biomolecules
- Important For Structural Biology And Drug Design
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Advanced Research Instruments (Auto Analyzer) | The Auto Analyzer in NIPER Kolkata’s laboratories streamlines the process of conducting various biochemical and chemical assays, enabling high-throughput and accurate measurements. This automated system significantly increases efficiency and reproducibility in research, reducing manual errors and saving time. It is particularly useful for routine analyses and large-scale screening in areas such as toxicology, pharmacology, and clinical chemistry. | - Automated Analytical System
- Performs High-throughput Measurements Of Various Parameters
- Efficient For Routine Biochemical And Chemical Assays
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Advanced Research Instruments (Automatic Tissue Processor) | The Automatic Tissue Processor at NIPER Kolkata facilitates the rapid and consistent preparation of tissue samples for histological and pathological examinations. This automated system streamlines the critical steps of fixation, dehydration, clearing, and infiltration, ensuring high-quality tissue sections for accurate diagnosis and research. It is an indispensable tool for studies involving tissue morphology, disease progression, and therapeutic effects in animal models. | - Automated System For Tissue Processing
- Prepares Tissue Samples For Microscopic Examination
- Essential For Histology And Pathology Studies
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Advanced Research Instruments (ITC) | NIPER Kolkata is equipped with an Isothermal Titration Calorimeter (ITC), a powerful biophysical technique used to directly measure the heat released or absorbed during molecular interactions. This instrument provides comprehensive thermodynamic information, including binding affinity, stoichiometry, enthalpy, and entropy. It is an essential tool for drug discovery and development, enabling researchers to characterize the binding of drug candidates to their targets and understand the underlying mechanisms. | - Isothermal Titration Calorimeter (Itc)
- Measures Thermodynamic Parameters Of Binding Interactions
- Critical For Drug-ligand Binding And Enzyme Kinetics
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Advanced Research Instruments (Flash Chromatography) | The Flash Chromatography system available at NIPER Kolkata is an efficient and rapid purification technique widely used for isolating compounds from reaction mixtures or natural extracts. This automated system accelerates the purification process, yielding high purity compounds essential for further characterization and biological evaluation. It significantly enhances productivity in synthetic chemistry and natural product research, supporting the isolation of novel drug candidates. | - Automated Chromatography System
- Rapid Purification Of Synthesized Compounds And Natural Products
- High Efficiency And Resolution For Separation
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Advanced Research Instruments (Electrochemical Workstation) | NIPER Kolkata's laboratories feature an Electrochemical Workstation, a versatile instrument for conducting a wide range of electrochemical studies. This workstation is instrumental in analyzing redox reactions, developing novel electrochemical sensors, and characterizing the electronic properties of materials relevant to pharmaceutical applications. It supports advanced research in electroanalytical chemistry, offering precise control and measurement for various electrochemical techniques. | - Versatile Platform For Electrochemical Analysis
- Used For Studying Redox Reactions And Sensor Development
- Supports Electroanalytical Chemistry Research
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Advanced Research Instruments (Inverted Fluorescence Microscope) | The Inverted Fluorescence Microscope at NIPER Kolkata is an advanced imaging system crucial for visualizing biological samples with high resolution and sensitivity. It is particularly suited for live cell imaging, allowing researchers to observe cellular processes in real-time without disturbing the cells. This microscope is indispensable for studies in cell biology, pharmacology, and toxicology, aiding in the understanding of drug effects and cellular mechanisms. | - Microscope With Fluorescence Imaging Capabilities
- Ideal For Live Cell Imaging And Tissue Analysis
- Supports Studies In Cell Biology And Pharmacology
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Advanced Research Instruments (Centrifuge & Ultra-Weighing Balance) | NIPER Kolkata is equipped with centrifuges for efficient separation of mixtures based on density, and ultra-weighing balances ensuring highly precise mass measurements. These fundamental tools are essential across all laboratory disciplines, from preparing samples for analytical instruments to formulating precise chemical solutions. Their presence underpins the accuracy and reliability of experimental results, vital for robust scientific research. | - Centrifuges For Separation Of Components
- Ultra-weighing Balance For Precise Mass Measurements
- Essential For Sample Preparation And Analytical Accuracy
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Advanced Research Instruments (CO2 Incubator) | The CO2 Incubator at NIPER Kolkata provides a precisely controlled environment crucial for successful cell culture and microbiological studies. It maintains optimal temperature, humidity, and carbon dioxide levels, mimicking physiological conditions necessary for cell growth and proliferation. This facility is indispensable for research involving drug screening, vaccine development, and understanding cellular responses to various stimuli. | - Controlled Environment For Cell Culture
- Maintains Optimal Temperature, Humidity, And Co2 Levels
- Essential For Cellular And Microbiological Studies
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Advanced Research Instruments (UV-Visible Spectrophotometer) | NIPER Kolkata's laboratories are equipped with a UV-Visible Spectrophotometer, a versatile instrument used for the quantitative analysis of compounds based on their light absorption properties. This spectrophotometer is widely employed for determining concentrations, monitoring reaction kinetics, and characterizing substances in solution. It is a fundamental tool for quality control, pharmaceutical analysis, and various biochemical assays, providing quick and reliable data. | - Measures Light Absorption In Uv-visible Range
- Used For Quantitative Analysis Of Compounds
- Essential For Concentration Determination And Reaction Monitoring
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Advanced Research Instruments (FACS) | The Fluorescence-Activated Cell Sorting (FACS) system at NIPER Kolkata offers advanced capabilities for high-throughput cell analysis and precise cell sorting based on their fluorescent properties. This powerful instrument is indispensable for immunology studies, stem cell research, and drug discovery, allowing researchers to isolate specific cell populations for detailed investigation. It significantly accelerates research on cellular mechanisms and responses to therapeutic interventions. | - Fluorescence-activated Cell Sorting (Facs) System
- Enables High-throughput Cell Analysis And Sorting
- Crucial For Immunology, Stem Cell Research, And Drug Discovery
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Advanced Research Instruments (Rotary Evaporator) | NIPER Kolkata's labs include Rotary Evaporators, fundamental equipment used for efficient and gentle removal of solvents from samples by evaporation under vacuum. These instruments are indispensable in synthetic organic chemistry, natural product isolation, and pharmaceutical formulation for concentrating solutions, recovering solvents, and preparing solid compounds. They ensure the integrity of heat-sensitive compounds by operating at lower temperatures. | - Efficient Solvent Removal From Samples
- Used For Concentrating Solutions And Drying Powders
- Standard Equipment In Synthetic And Natural Product Chemistry
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Advanced Research Instruments (Lyophilizer) | The Lyophilizer, or freeze-dryer, at NIPER Kolkata is vital for preserving heat-sensitive and biological samples by removing water through sublimation. This process is crucial for long-term storage of chemicals, proteins, and cell lines, as well as for preparing stable pharmaceutical formulations like injectable powders. It ensures the integrity and activity of delicate materials, extending their shelf life and facilitating research involving unstable compounds. | - Freeze-drying Equipment
- Preserves Heat-sensitive And Biological Samples
- Used For Long-term Storage And Preparation Of Dosage Forms
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Advanced Research Instruments (Chemi Doc) | NIPER Kolkata utilizes a Chemi Doc system, a sophisticated gel documentation unit designed for capturing high-quality images of electrophoresis gels and blots. This system is crucial for molecular biology research, including DNA, RNA, and protein analysis, allowing researchers to visualize and quantify experimental results from techniques like Western blotting and gel electrophoresis. It provides precise documentation necessary for publication and further scientific investigation. | - Gel Documentation System
- Captures High-quality Images Of Electrophoresis Gels
- Essential For Molecular Biology And Protein Analysis
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Advanced Research Instruments (Probe Sonicator) | The Probe Sonicator in NIPER Kolkata's laboratories is an essential tool for sample preparation, utilizing high-frequency ultrasonic waves to disrupt cells, tissues, and homogenize solutions. It is widely used in biochemistry, molecular biology, and nanotechnology for DNA shearing, protein extraction, and nanoparticle dispersion. The controlled sonication provided ensures efficient sample processing, vital for downstream analytical techniques and research applications. | - Uses Ultrasonic Waves For Cell Disruption And Homogenization
- Ideal For Sample Preparation In Biochemical And Molecular Biology Studies
- Efficient And Controlled Sonication
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Advanced Research Instruments (QPCR) | NIPER Kolkata is equipped with a Quantitative Polymerase Chain Reaction (qPCR) system, a highly sensitive molecular biology tool that measures DNA or RNA amplification in real-time. This instrument is indispensable for gene expression analysis, pathogen detection, and genetic variation studies, offering precise quantification and high accuracy. It plays a crucial role in pharmaceutical research, including drug efficacy studies and biomarker discovery. | - Quantitative Polymerase Chain Reaction (Qpcr) System
- Measures Dna/rna Amplification In Real-time
- Critical For Gene Expression Analysis And Pathogen Detection
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Advanced Research Instruments (Electroporator) | The Electroporator at NIPER Kolkata is a key instrument for cell engineering and gene transfer, facilitating the efficient delivery of biomolecules into cells through transient pore formation in cell membranes using electrical pulses. This technology is vital for introducing DNA, RNA, and proteins into various cell types, with broad applications in gene therapy, drug discovery, and vaccine development. It enables researchers to manipulate cellular functions for therapeutic purposes. | - Delivers Electrical Pulses For Cell Membrane Permeabilization
- Used For Efficient Delivery Of Dna, Rna, And Proteins Into Cells
- Applications In Gene Therapy And Cell Engineering
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Advanced Research Instruments (Thermocycler) | NIPER Kolkata's laboratories are equipped with Thermocyclers, indispensable instruments that automate the Polymerase Chain Reaction (PCR), a cornerstone technique in molecular biology. By precisely controlling rapid temperature changes, the thermocycler enables the amplification of specific DNA sequences for various applications, including gene cloning, sequencing, and genetic diagnostics. It is a fundamental tool that underpins a vast array of research in pharmaceutical sciences. | - Performs Polymerase Chain Reaction (Pcr)
- Automates Rapid Heating And Cooling Of Samples
- Essential For Dna Amplification And Molecular Cloning
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Advanced Research Instruments (BOD Incubator) | The BOD Incubator at NIPER Kolkata provides a stable and controlled temperature environment crucial for various biological and pharmaceutical studies. It is primarily used for cultivating microorganisms, performing biochemical oxygen demand tests in environmental analysis, and conducting long-term stability studies of drug formulations. This incubator ensures optimal conditions for precise and reproducible experimental outcomes in microbiology and pharmaceutical quality control. | - Biochemical Oxygen Demand (Bod) Incubator
- Maintains Precise Temperature For Biological Sample Incubation
- Used For Microbiological Cultures And Stability Studies
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Advanced Research Instruments (Plethysmometer) | NIPER Kolkata's preclinical pharmacology labs utilize the Plethysmometer, an instrument designed to accurately measure paw volume in rodents, primarily used in evaluating the efficacy of anti-inflammatory and analgesic drugs. This device is critical for inducing and monitoring paw edema, a standard model for assessing inflammatory responses. It plays a significant role in the initial screening and development of new therapeutic agents. | - Measures Paw Edema In Rodents
- Used In Anti-inflammatory Drug Screening
- Essential For Preclinical Pharmacology Studies
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Animal House | NIPER Kolkata maintains an Animal House, a crucial facility for conducting preclinical research and drug testing. This dedicated space provides a controlled environment for housing laboratory animals, ensuring their well-being and adherence to ethical guidelines. It is indispensable for studies requiring in vivo models, contributing significantly to the development and safety assessment of new pharmaceutical compounds. | - Dedicated Facility For Housing Laboratory Animals
- Supports Preclinical Research And Drug Testing
- Ensures Ethical Animal Care Standards
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Center for Marine Therapeutics | The Center for Marine Therapeutics at NIPER Kolkata is a specialized research hub dedicated to tackling critical health challenges posed by drug-resistant cancer, bacteria, and viruses. Established with significant funding support from governmental departments, this center leverages marine resources for novel therapeutic discoveries. It emphasizes cutting-edge research to develop innovative solutions and contribute to global health. | - Focuses On Drug-resistant Cancer, Bacteria, And Viruses
- Receives Funding From Department Of Science & Technology And Department Of Pharmaceuticals
- Conducts Advanced Research In Marine-derived Compounds
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