

M-SC in Biochemistry at VELS Institute of Science, Technology & Advanced Studies (VISTAS)


Chennai, Tamil Nadu
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About the Specialization
What is Biochemistry at VELS Institute of Science, Technology & Advanced Studies (VISTAS) Chennai?
This M.Sc Biochemistry program at Vels Institute of Science Technology and Advanced Studies focuses on a deep understanding of the chemical processes within living organisms. It delves into the intricate molecular mechanisms underpinning life, from biomolecules to complex metabolic pathways. Given India''''s burgeoning biotechnology and pharmaceutical sectors, a strong foundation in biochemistry is crucial for innovation and research in health, agriculture, and industry. The program differentiates itself by integrating core biochemical principles with advanced analytical and molecular techniques, preparing students for cutting-edge roles.
Who Should Apply?
This program is ideal for science graduates, particularly those with a B.Sc in Biochemistry, Biotechnology, or allied life sciences, who seek to deepen their knowledge. It suits fresh graduates aspiring for research, diagnostic, or R&D roles in pharmaceutical and biotech companies. Working professionals in related fields looking to upskill with advanced biochemical expertise or career changers aiming to transition into the rapidly evolving life sciences industry would also find this program highly beneficial. A strong aptitude for scientific inquiry and laboratory work is a prerequisite.
Why Choose This Course?
Graduates of this program can expect diverse career paths in India, including roles as Research Scientists, Clinical Biochemists, Analytical Scientists, and Quality Control/Assurance specialists in pharmaceutical, food, and clinical diagnostic sectors. Entry-level salaries typically range from INR 3-5 lakhs per annum, with experienced professionals earning INR 8-15 lakhs and beyond. Growth trajectories often lead to senior scientist, R&D management, or academic positions. The program also aligns with prerequisites for professional certifications in clinical laboratory sciences and enables further doctoral studies.

Student Success Practices
Foundation Stage
Build Strong Conceptual Foundations- (Semester 1)
Focus intensely on mastering core concepts in Biomolecules, Analytical Biochemistry, Cell Biology, and Physiology. Regularly review lecture notes, solve practice problems, and clarify doubts promptly with faculty. Utilize online resources for conceptual understanding and self-assessment quizzes.
Tools & Resources
NPTEL lectures for Biochemistry, Khan Academy, Lehninger Principles of Biochemistry textbook, Peer study groups
Career Connection
A robust understanding of fundamentals is critical for all advanced subjects and forms the bedrock for problem-solving in research and diagnostic roles.
Develop Essential Laboratory Skills- (Semester 1)
Actively engage in all practical sessions for Analytical Biochemistry, Cell Biology, and Physiology. Pay meticulous attention to experimental design, accurate execution, data recording, and analysis. Seek additional lab time or volunteer for faculty projects to gain more hands-on experience.
Tools & Resources
Lab manuals, YouTube tutorials for specific techniques, Mentoring from senior students or lab technicians
Career Connection
Proficiency in laboratory techniques is indispensable for R&D, quality control, and clinical diagnostic roles in the industry.
Cultivate Scientific Reading & Critical Thinking- (Semester 1)
Beyond textbooks, start reading review articles and introductory research papers related to your subjects. Attend departmental seminars and discuss findings with peers and professors. Practice summarizing complex information and identifying key arguments to foster critical thinking.
Tools & Resources
PubMed, Google Scholar, University library resources, Departmental seminar series
Career Connection
This skill is vital for research, literature review, and staying updated with advancements, preparing for higher studies or R&D roles.
Intermediate Stage
Master Core Metabolic & Molecular Techniques- (Semester 2)
Deepen understanding and practical skills in Intermediary Metabolism and Molecular Biology. Focus on linking metabolic pathways and understanding the mechanisms of DNA/RNA manipulation. Practice data interpretation from molecular biology experiments.
Tools & Resources
Molecular Biology kits, Simulation software for metabolic pathways, Advanced biochemistry textbooks, Online courses on PCR and cloning
Career Connection
These skills are directly applicable in pharmaceutical R&D, biotechnology companies, and genetic diagnostics, offering direct entry into specialized roles.
Explore Clinical Applications & Diagnostic Principles- (Semester 2)
Pay close attention to Clinical Biochemistry and Immunology, understanding the diagnostic relevance of various assays and disease markers. Consider shadowing in a diagnostic lab or hospital''''s pathology department if opportunities arise to see real-world applications.
Tools & Resources
Clinical Biochemistry textbooks, Case studies, Diagnostic lab visits (if permissible)
Career Connection
Essential for careers in clinical diagnostics, medical labs, and pharmaceutical research focusing on disease mechanisms and drug development.
Begin Networking & Professional Engagement- (Semester 2)
Actively participate in conferences, workshops, and seminars organized by the department or other institutions. Connect with guest speakers, faculty members, and senior students. Join relevant professional bodies (e.g., Society of Biological Chemists, India chapter) to expand your professional network.
Tools & Resources
LinkedIn, Professional society memberships, University career services events
Career Connection
Networking opens doors to internship opportunities, mentorship, and future job prospects in the Indian life sciences industry.
Advanced Stage
Engage in Intensive Research Project Work- (Semesters 3-4)
Dedicate significant effort to your Project Work (Phase I & II). Choose a research topic aligned with your career interests. Meticulously plan experiments, execute them, analyze data, and critically interpret results. Seek regular feedback from your mentor and refine your thesis.
Tools & Resources
Statistical software (R, SPSS), Research databases (PubMed, Scopus), Laboratory equipment, University research facilities, Mentor guidance
Career Connection
A strong research project is a key differentiator for R&D roles, academic positions, and demonstrating problem-solving capabilities to potential employers.
Specialize and Gain Advanced Skills- (Semesters 3-4)
Strategically choose electives (e.g., Cancer Biology, Neurochemistry, Food & Nutritional Biochemistry) that align with your career goals. Deep dive into the chosen area, pursuing advanced readings, attending specialized workshops, and potentially pursuing minor projects in that domain.
Tools & Resources
Advanced subject-specific journals, Specialized online courses, Industry reports, Expert lectures
Career Connection
Specialization makes you a more attractive candidate for specific industry segments (e.g., oncology research, food industry R&D, neuropharma).
Prepare for Industry & Career Launch- (Semesters 3-4)
Actively participate in campus placement drives, refine your resume and cover letter, and practice interview skills (technical and HR). Network with alumni and industry professionals for insights and referrals. Consider competitive exams like CSIR NET/GATE for research or academic careers.
Tools & Resources
Career services cell, Mock interview sessions, Online job portals (Naukri.com, LinkedIn), Previous year''''s question papers for competitive exams
Career Connection
This ensures a smooth transition into employment or higher education, maximizing your chances of securing a desirable position in India''''s competitive job market.
Program Structure and Curriculum
Eligibility:
- B.Sc. Degree with Biochemistry / Biotechnology / Microbiology / Plant Biology & Biotechnology / Zoology / Botany / Chemistry / Nutrition & Dietetics / Home Science / Food Science and Quality Control / B.Pharm / B.Sc. Agriculture / B.F.Sc. from recognized Universities.
Duration: 4 semesters / 2 years
Credits: 90 Credits
Assessment: Internal: 40% (for Theory), 60% (for Practical), External: 60% (for Theory), 40% (for Practical)
Semester-wise Curriculum Table
Semester 1
| Subject Code | Subject Name | Subject Type | Credits | Key Topics |
|---|---|---|---|---|
| 11SBIC101 | Biomolecules | Core | 4 | Chemistry of Carbohydrates, Structure and function of Lipids, Amino acids and Protein structure, Enzyme classification and kinetics, Nucleic acids structure and function |
| 11SBIC102 | Analytical Biochemistry | Core | 4 | Principles of Spectroscopy, Chromatographic techniques, Electrophoresis techniques, Centrifugation methods, Immunochemical techniques |
| 11SBIC103 | Cell Biology | Core | 4 | Prokaryotic and Eukaryotic cell organization, Structure and function of cellular organelles, Cell signaling mechanisms, Cell cycle and its regulation, Apoptosis and Cancer biology |
| 11SBIC104 | Physiology | Core | 4 | Physiology of digestive system, Respiratory system functions, Circulatory system and blood components, Excretory system and kidney function, Nervous and Endocrine systems |
| 11SBICP11 | Lab in Analytical Biochemistry | Practical | 4 | Qualitative tests for biomolecules, Quantitative estimation of carbohydrates, Protein and lipid estimation methods, Paper and thin layer chromatography, Spectrophotometric analysis |
| 11SBICP12 | Lab in Cell Biology and Physiology | Practical | 4 | Microscopic examination of cells, Blood cell counting techniques, Haemoglobin estimation, RBC fragility test, Protein electrophoresis |
Semester 2
| Subject Code | Subject Name | Subject Type | Credits | Key Topics |
|---|---|---|---|---|
| 11SBIC201 | Intermediary Metabolism | Core | 4 | Bioenergetics and ATP production, Carbohydrate metabolism pathways, Lipid metabolism and fatty acid oxidation, Amino acid and nucleotide metabolism, Integration of metabolic pathways |
| 11SBIC202 | Molecular Biology | Core | 4 | DNA replication mechanisms, Transcription and RNA synthesis, Translation and protein synthesis, Regulation of gene expression, Recombinant DNA technology principles |
| 11SBIC203 | Immunology | Core | 4 | Innate and adaptive immunity, Antigens and antibodies structure, Major Histocompatibility Complex, Cell mediated and humoral immunity, Immunological techniques |
| 11SBIC204 | Clinical Biochemistry | Core | 4 | Specimen collection and analysis, Liver function tests, Kidney function tests, Cardiac markers in disease, Biochemistry of diabetes mellitus |
| 11SBICP21 | Lab in Intermediary Metabolism | Practical | 4 | Enzyme assay for amylase and lipase, Estimation of blood glucose, Estimation of urea and creatinine, Estimation of serum proteins, Analysis of urine components |
| 11SBICP22 | Lab in Molecular Biology and Immunology | Practical | 4 | DNA and RNA isolation, Polymerase Chain Reaction (PCR), Agarose gel electrophoresis, Enzyme-Linked Immunosorbent Assay (ELISA), Ouchterlony immunodiffusion |
Semester 3
| Subject Code | Subject Name | Subject Type | Credits | Key Topics |
|---|---|---|---|---|
| 11SBIC301 | Enzyme Technology | Core | 4 | Enzyme kinetics and mechanism, Enzyme inhibition studies, Enzyme purification techniques, Immobilized enzymes and applications, Industrial applications of enzymes |
| 11SBIC302 | Genetic Engineering | Core | 4 | Cloning vectors and hosts, Restriction enzymes and ligases, Gene cloning strategies, Gene libraries and screening, Gene transfer methods in eukaryotes |
| 11SBICE305 | Medical Biochemistry | Elective | 4 | Diagnostic markers for diseases, Biochemical basis of genetic disorders, Nutritional deficiencies and disorders, Biochemistry of cardiovascular diseases, Therapeutic interventions in metabolic disorders |
| 11SBICE306 | Food & Nutritional Biochemistry | Elective | 4 | Chemistry of macronutrients, Vitamins and minerals, Balanced diet and dietary requirements, Food spoilage and preservation, Food additives and contaminants |
| 11SBICE307 | Plant Biochemistry | Elective | 4 | Photosynthesis pathways, Nitrogen metabolism in plants, Plant growth hormones, Secondary metabolites in plants, Plant responses to stress |
| 11SBICP31 | Lab in Enzyme Technology and Genetic Engineering | Practical | 4 | Determination of enzyme activity, Calculation of Km and Vmax, DNA ligation and transformation, Plasmid isolation and restriction analysis, Gene cloning experiment |
| 11SBIC3PR | Project Work – Phase I | Project | 4 | Literature survey and review, Identification of research problem, Formulation of hypothesis, Designing experimental methodology, Ethical considerations in research |
Semester 4
| Subject Code | Subject Name | Subject Type | Credits | Key Topics |
|---|---|---|---|---|
| 11SBIC401 | Advanced Clinical Biochemistry | Core | 4 | Biochemical markers of disease, Molecular diagnostics in clinical practice, Pharmacogenomics principles, Oxidative stress and antioxidants, Biomarkers in cancer and neurological disorders |
| 11SBICE404 | Cancer Biology | Elective | 4 | Hallmarks of cancer, Oncogenes and tumor suppressor genes, Apoptosis and cell death pathways, Metastasis and angiogenesis, Cancer therapy strategies |
| 11SBICE405 | Neurochemistry | Elective | 4 | Neurotransmitters and their synthesis, Neuroreceptors and signal transduction, Synaptic transmission mechanisms, Biochemistry of neurodegenerative diseases, Neuropharmacology principles |
| 11SBICE406 | Environmental Biochemistry | Elective | 4 | Bioremediation of pollutants, Metabolism of xenobiotics, Ecotoxicology and environmental impact, Biochemistry of global warming, Biomonitoring of environmental pollution |
| 11SBIC4PR | Project Work – Phase II | Project | 12 | Data collection and experimentation, Statistical analysis of results, Interpretation of findings, Thesis writing and documentation, Presentation and viva-voce |




