
M-SC in Biotechnology at SRM Institute of Science and Technology


Chengalpattu, Tamil Nadu
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About the Specialization
What is Biotechnology at SRM Institute of Science and Technology Chengalpattu?
This M.Sc Biotechnology program at SRM Institute of Science and Technology, Chengalpattu, focuses on advanced biological sciences, blending theoretical knowledge with practical applications. The curriculum emphasizes cutting-edge areas like genetic engineering, immunology, and bioprocess technology, preparing students for diverse roles in India''''s rapidly expanding biotech and pharmaceutical sectors. The program''''s comprehensive approach addresses contemporary industry demands.
Who Should Apply?
This program is ideal for science graduates, particularly those with a background in biotechnology, microbiology, biochemistry, or related life sciences, seeking entry into the thriving biotech industry. It also caters to working professionals aiming to upskill or career changers transitioning into research, development, or production roles within the Indian healthcare and bio-manufacturing sectors.
Why Choose This Course?
Graduates of this program can expect diverse career paths in India, including roles in R&D, quality control, manufacturing, and academia. Entry-level salaries typically range from INR 3-6 lakhs per annum, with experienced professionals earning significantly more. The program aligns with growth trajectories in Indian companies, offering opportunities in areas like vaccine development, diagnostics, and biopharmaceutical production.

Student Success Practices
Foundation Stage
Master Core Biotechnology Concepts- (Semester 1-2)
Dedicate time to thoroughly understand fundamental principles in biochemistry, cell, and molecular biology. Utilize textbooks, online lectures (e.g., NPTEL, Khan Academy), and peer study groups to solidify knowledge. Focus on conceptual clarity over rote learning.
Tools & Resources
NPTEL courses on Biochemistry/Cell Biology, Key textbooks by Lehninger, Alberts, Peer study groups
Career Connection
A strong foundation is crucial for excelling in advanced subjects, cracking competitive exams (CSIR NET, GATE) for research, and performing well in technical interviews for biotech R&D roles in India.
Develop Lab Proficiency and Safety Habits- (Semester 1-2)
Actively participate in all lab sessions, seeking to understand the ''''why'''' behind each step. Practice meticulous record-keeping and strictly adhere to biosafety protocols. Volunteer for extra lab hours if possible to gain additional hands-on experience.
Tools & Resources
Lab manuals, Demonstration videos, Biosafety guidelines (e.g., DBT India guidelines)
Career Connection
Practical lab skills are highly valued by Indian biotech companies for R&D, quality control, and manufacturing positions. Strict adherence to safety is mandatory for all industry roles.
Cultivate Analytical and Statistical Thinking- (Semester 1-2)
Pay close attention during Research Methodology and Biostatistics. Practice solving problems, interpreting data, and applying statistical tests. Utilize software like R or SPSS early on. Engage in critical thinking during scientific discussions.
Tools & Resources
R/Python for Biostatistics, Statistical textbooks, Online problem sets
Career Connection
Essential for research positions, data analysis roles in pharmaceutical companies, and for designing robust experiments, a critical skill for any biotechnologist in India.
Intermediate Stage
Engage in Mini-Projects and Internships- (Semester 3-4 (Summer breaks))
Seek out faculty for short-term research projects or apply for internships at local biotech companies or research institutions during semester breaks. This helps apply classroom knowledge to real-world problems and builds a professional network.
Tools & Resources
Faculty research labs, Biotech companies in Chennai/Bangalore/Hyderabad, DBT STAR College Scheme
Career Connection
Practical exposure during internships significantly boosts employability and provides valuable experience for securing final placements in Indian biotech firms.
Specialize and Network Effectively- (Semester 3-4)
Based on elective choices, delve deeper into a specific area like immunology, genetic engineering, or bioprocess. Attend workshops, seminars, and industry conferences. Connect with professionals on platforms like LinkedIn, focusing on Indian biotech leaders.
Tools & Resources
LinkedIn, Biotech industry conferences (e.g., BioAsia), Specialized journals
Career Connection
Specialized skills make you a more targeted candidate. Networking opens doors to job opportunities, mentorship, and insights into specific industry demands in India.
Develop Scientific Communication Skills- (Semester 3-4)
Practice presenting research findings, writing scientific reports, and preparing clear, concise lab summaries. Participate in college debates or scientific presentation competitions. Focus on articulating complex biological concepts effectively.
Tools & Resources
Grammarly, Mendeley/Zotero for referencing, Presentation software
Career Connection
Strong communication is vital for presenting research, writing grant proposals, and collaborating with diverse teams in both academia and industry in India.
Advanced Stage
Undertake a High-Impact Dissertation Project- (Semester 4)
Choose a dissertation topic aligned with your career aspirations and current industry trends. Work diligently, seeking regular feedback from your guide. Aim for publishable quality research or a patentable idea, if possible. This forms the cornerstone of your CV.
Tools & Resources
Research labs within SRMIST, Collaborating industry partners, Scopus/PubMed for literature
Career Connection
A strong project is your primary credential for research-intensive roles and provides concrete evidence of your problem-solving abilities to Indian employers and Ph.D. admissions committees.
Intensive Placement and Interview Preparation- (Semester 4)
Begin mock interviews, practice aptitude tests, and refine your resume and cover letter. Understand common biotech interview questions, particularly those related to your project work and specialization. Focus on both technical and soft skills.
Tools & Resources
Career services at SRMIST, Online aptitude test platforms, Biotech interview question guides
Career Connection
Directly prepares you for campus placements and off-campus hiring drives by leading Indian and multinational biotech companies, maximizing job offer potential.
Explore Entrepreneurship or Higher Studies- (Semester 4 onwards)
If interested in entrepreneurship, develop a business plan for a biotech startup, exploring incubation centers. For higher studies, prepare for competitive exams like UGC NET, CSIR JRF, or international GRE/TOEFL. Explore Ph.D. opportunities in India and abroad.
Tools & Resources
SRMIST incubation center, Startup India resources, Exam preparation materials
Career Connection
This path leads to leadership roles, self-employment, or advanced research careers, contributing to India''''s scientific and economic growth, fulfilling diverse long-term career goals.
Program Structure and Curriculum
Eligibility:
- Bachelor''''s Degree (B.Sc./B.Tech.) in Biotechnology / Industrial Biotechnology / Genetic Engineering / Biochemistry / Microbiology / Agriculture / Botany / Zoology / Plant Science / Animal Science / Chemistry / Physics / Pharmacy / B.V.Sc. / B.F.Sc. / M.B.B.S. / B.D.S. / B.P.T. / B.O.T. / B.Pharma.
Duration: 2 years (4 semesters)
Credits: Minimum 75 Credits
Assessment: Internal: 40%, External: 60%
Semester-wise Curriculum Table
Semester 1
| Subject Code | Subject Name | Subject Type | Credits | Key Topics |
|---|---|---|---|---|
| BT2101 | Bioanalytical Techniques | Core | 4 | Spectroscopy Principles and Applications, Chromatographic Separations, Electrophoretic Techniques, Centrifugation Methods, Immunological Assays, Radioisotope Techniques |
| BT2102 | Cell and Molecular Biology | Core | 4 | Eukaryotic Cell Structure and Organelles, Cell Cycle Regulation, DNA Replication Mechanisms, Gene Transcription Processes, mRNA Translation and Protein Synthesis, Gene Expression Control |
| BT2103 | Biochemistry | Core | 4 | Structure and Function of Biomolecules, Carbohydrate Metabolism, Lipid Metabolism, Protein Metabolism and Nitrogen Cycle, Enzyme Kinetics and Mechanism, Bioenergetics and Oxidative Phosphorylation |
| BT21L1 | Bioanalytical Techniques and Biochemistry Lab | Lab | 2 | Spectrophotometric Assays, Chromatographic Separation Practicals, Enzyme Activity Measurement, Biomolecule Quantification, Electrophoresis Hands-on, pH and Buffer Preparation |
| BT21L2 | Cell and Molecular Biology Lab | Lab | 2 | Cell Counting and Viability, DNA and RNA Isolation, Polymerase Chain Reaction (PCR), Agarose Gel Electrophoresis, Microscopy Techniques, Bacterial Transformation |
| BT2104 | Research Methodology and Biostatistics | Core | 4 | Research Design and Planning, Data Collection Methods, Measures of Central Tendency, Hypothesis Testing (t-test, ANOVA), Correlation and Regression Analysis, Scientific Report Writing |
Semester 2
| Subject Code | Subject Name | Subject Type | Credits | Key Topics |
|---|---|---|---|---|
| BT2105 | Genetic Engineering and Genomics | Core | 4 | Recombinant DNA Technology Tools, Cloning Vectors and Gene Libraries, Gene Expression Systems, DNA Sequencing Technologies, Genome Mapping and Annotation, Proteomics and Metabolomics |
| BT2106 | Immunology | Core | 4 | Components of the Immune System, Innate and Adaptive Immunity, Antibody Structure and Function, Major Histocompatibility Complex, Hypersensitivity Reactions, Autoimmunity and Immunodeficiencies |
| BT2107 | Enzyme Technology | Core | 4 | Enzyme Kinetics and Mechanisms, Enzyme Purification and Characterization, Enzyme Immobilization Techniques, Industrial Enzyme Production, Applications of Enzymes in Industry, Enzyme Engineering and Design |
| BT21L3 | Genetic Engineering and Genomics Lab | Lab | 2 | Plasmid DNA Isolation, Restriction Digestion and Ligation, Bacterial Transformation and Selection, PCR Amplification, DNA Gel Electrophoresis, Gene Cloning Practicals |
| BT21L4 | Immunology and Enzyme Technology Lab | Lab | 2 | ELISA Technique, Radial Immunodiffusion, Blood Grouping, Enzyme Activity Assays, Enzyme Immobilization Practical, Western Blotting Principles |
| BT21E01 | Cancer Biology | Elective | 3 | Molecular Basis of Cancer, Oncogenes and Tumor Suppressor Genes, Cell Cycle and Apoptosis, Metastasis and Angiogenesis, Cancer Diagnostics and Prognosis, Cancer Therapeutics and Drug Development |
| BT21E02 | Animal Cell Culture Technology | Elective | 3 | Fundamentals of Animal Cell Culture, Cell Lines and Primary Cultures, Culture Media and Supplements, Aseptic Techniques and Contamination Control, Cell Proliferation and Viability Assays, Scale-up and Bioreactor Systems |
| BT21E03 | Stem Cell Biology and Regenerative Medicine | Elective | 3 | Types of Stem Cells, Pluripotency and Differentiation, Embryonic and Adult Stem Cells, Induced Pluripotent Stem Cells (iPSCs), Tissue Engineering Principles, Ethical Considerations in Stem Cell Research |
| BT21E04 | Food Biotechnology | Elective | 3 | Microbial Fermentation in Food, Food Additives and Ingredients, Food Safety and Quality Control, Probiotics and Prebiotics, Genetically Modified Foods, Biotechnological Processing in Food Industry |
| BT21E05 | Environmental Biotechnology | Elective | 3 | Bioremediation of Pollutants, Waste Water Treatment, Solid Waste Management, Biofuels Production, Environmental Monitoring Techniques, Microbial Ecology and Biogeochemical Cycles |
| BT21E06 | Medical Biotechnology | Elective | 3 | Biotechnological Diagnostics, Gene Therapy Approaches, Drug Discovery and Development, Vaccine Technologies, Tissue Engineering for Medical Applications, Personalized Medicine |
| BT21E07 | Nano Biotechnology | Elective | 3 | Nanomaterials in Biology, Synthesis of Nanoparticles, Nanobioconjugates, Drug Delivery Systems, Biosensors and Diagnostics, Applications in Medicine and Agriculture |
| BT21E08 | Computational Biology and Bioinformatics | Elective | 3 | Biological Databases (NCBI, UniProt), Sequence Alignment Algorithms, Phylogenetic Tree Construction, Protein Structure Prediction, Molecular Docking, Genomics and Transcriptomics Analysis |
| BT21E09 | Pharmaceutical Biotechnology | Elective | 3 | Biopharmaceuticals Production, Drug Development Process, Pharmacogenomics, Clinical Trials and Regulations, Vaccine Manufacturing, Monoclonal Antibodies |
| BT21E10 | Microbial Biotechnology | Elective | 3 | Microbial Diversity and Applications, Industrial Microorganisms, Fermentation Products, Biocatalysis by Microbes, Probiotics and Gut Microbiome, Microbial Diagnostics |
| BT21E11 | Marine Biotechnology | Elective | 3 | Marine Organisms and Biodiversity, Bioactive Compounds from Marine Sources, Aquaculture Biotechnology, Marine Bioremediation, Marine Genomics and Proteomics, Algal Biotechnology |
| BT21E12 | Agri-Biotechnology | Elective | 3 | Crop Improvement through Biotechnology, Transgenic Plants Development, Biofertilizers and Biopesticides, Stress Tolerance in Crops, Plant Disease Resistance, Post-Harvest Biotechnology |
| BT21E13 | Industrial Biotechnology | Elective | 3 | Bioprocess Optimization, Biofuels Production, Biopolymers and Bioplastics, Industrial Enzyme Applications, Fermentation Technology, Downstream Processing in Industry |
| BT21E14 | Bio-Entrepreneurship | Elective | 3 | Business Plan Development, Market Analysis in Biotechnology, Intellectual Property Rights Management, Funding and Venture Capital, Biotech Startup Ecosystem, Regulatory Compliance for Bio-businesses |
| BT21E15 | IPR & Regulatory Affairs | Elective | 3 | Intellectual Property Rights Overview, Patents, Trademarks, Copyrights, Regulatory Agencies (FDA, EMA, CDSCO), Product Approval Process, Good Manufacturing Practices (GMP), Biotechnology Regulations |
Semester 3
| Subject Code | Subject Name | Subject Type | Credits | Key Topics |
|---|---|---|---|---|
| BT2108 | Bioprocess Technology | Core | 4 | Principles of Fermentation, Bioreactor Design and Operation, Sterilization Techniques, Upstream Processing, Downstream Processing, Bioproduct Manufacturing |
| BT2109 | Plant Biotechnology | Core | 4 | Plant Tissue Culture Techniques, Plant Genetic Engineering, Transgenic Plants and their Applications, Secondary Metabolite Production, Crop Improvement Strategies, Molecular Markers in Plants |
| BT21L5 | Bioprocess Technology Lab | Lab | 2 | Fermentation Media Preparation, Batch and Fed-Batch Fermentation, Bioreactor Operation, Product Recovery and Purification, Cell Disruption Methods, Sterilization of Bioreactors |
| BT21L6 | Plant Biotechnology Lab | Lab | 2 | Aseptic Plant Culture, Callus Induction and Regeneration, Micropropagation of Plants, Agrobacterium-Mediated Transformation, DNA Isolation from Plants, Gene Expression Analysis in Plants |
| BT21V01 | Biosafety and Bioethics | Value Added Course | 2 | Biosafety Levels (BSL-1 to BSL-4), Risk Assessment in Biotechnology, Regulations for Genetically Modified Organisms (GMOs), Ethical Issues in Biotechnology, Intellectual Property Rights (IPR), Biopiracy and Benefit Sharing |
| BT21V02 | Basic Programming for Biologists | Value Added Course | 2 | Introduction to Python/R Programming, Data Types and Structures, Control Flow and Functions, Basic Bioinformatics Tools, Statistical Computing, Data Visualization in Biology |
| BT21V03 | Molecular Diagnostics | Value Added Course | 2 | Principles of PCR and its Variants, ELISA and Immunological Diagnostics, Microarray Technology, DNA Sequencing for Disease Diagnosis, Biosensors in Diagnostics, Clinical Applications of Molecular Diagnostics |
| BT21V04 | Protein Engineering | Value Added Course | 2 | Protein Structure and Function, Rational Protein Design, Directed Evolution Techniques, Modification of Enzyme Properties, Therapeutic Protein Development, Industrial Applications of Engineered Proteins |
| BT21V05 | Data Analytics for Biology | Value Added Course | 2 | Data Visualization Techniques, Statistical Software for Biological Data, Introduction to Machine Learning, Omics Data Analysis (Genomics, Proteomics), Big Data Concepts in Biology, Predictive Models for Biological Systems |
| BT21V06 | Scientific Writing | Value Added Course | 2 | Structure of a Research Paper, Effective Grant Writing, Avoiding Plagiarism, Citation and Referencing Styles, Thesis and Dissertation Writing, Oral Presentation Skills |
| BT21V07 | Bioinformatics Tools and Databases | Value Added Course | 2 | Major Biological Databases (GenBank, PDB), Sequence Alignment Tools (BLAST, FASTA), Primer Design Software, Molecular Docking Simulations, Protein Structure Visualization Tools, Genome Browsers |
| BT21V08 | Drug Design and Development | Value Added Course | 2 | Target Identification and Validation, Lead Discovery and Optimization, Pre-clinical Studies, Clinical Trial Phases, Pharmacokinetics and Pharmacodynamics, Regulatory Approval Process |
| BT21V09 | Artificial Intelligence in Biology | Value Added Course | 2 | Introduction to Machine Learning in Biology, Deep Learning Architectures, Neural Networks Applications, Image Analysis in Microscopy, Predictive Modeling in Drug Discovery, Genomic Data Analysis with AI |
Semester 4
| Subject Code | Subject Name | Subject Type | Credits | Key Topics |
|---|---|---|---|---|
| BT21P1 | Project Work / Dissertation | Project | 16 | Literature Review and Problem Identification, Experimental Design and Methodology, Data Collection and Analysis, Scientific Writing and Thesis Preparation, Oral Presentation of Findings, Troubleshooting and Optimization |
| BT2100 | Industrial Training / Internship | Internship | 0 | Practical Industry Exposure, Application of Theoretical Knowledge, Professional Skill Development, Networking Opportunities, Report Submission and Presentation, Understanding Industry Processes |




